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首页> Vaccine> The mucosal adjuvant effect of plant polysaccharides for induction of protective immunity against Helicobacter pylori infection.

The mucosal adjuvant effect of plant polysaccharides for induction of protective immunity against Helicobacter pylori infection.

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作者： Chang,Liu ^[1] ; Jiao,Luo ^[1] ; Ruo-Yi,Xue ^[1] ; Ling,Guo ^[2] ; Li,Nie ^[1] ; Sun,Li ^[1] ; Lu,Ji ^[1] ; Cong-Jia,Ma ^[1] ; Da-Qun,Chen ^[1] ; Kuan,Miao ^[1] ; Quan-Ming,Zou ^[3] ; Hai-Bo,Li ^[4]

作者单位： National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Chongqing 400038, PR China. ^[1] Chongqing Technical Center for Drug Evaluation & Certification, Chongqing 400014, PR China. ^[2] National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Chongqing 400038, PR China. Electronic address: qmzou@tmmu.edu.cn. ^[3] National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Chongqing 400038, PR China. Electronic address: lihaibo@tmmu.edu.cn. ^[4]

关键词 Helicobacter pylori Plant polysaccharides TLR2 activity mucosal adjuvant effect

主题词佐剂, 免疫(Adjuvants, Immunologic);投药, 鼻内(Administration, Intranasal);动物(Animals);女(雌)性(Female);螺杆菌感染(Helicobacter Infections);幽门螺杆菌(Helicobacter pylori);免疫法(Immunization);免疫球蛋白A(Immunoglobulin A);免疫球蛋白G(Immunoglobulin G);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);黏膜(Mucous Membrane);多糖类(Polysaccharides);Th1细胞(Th1 Cells);Th17细胞(Th17 Cells);尿素酶(Urease);接种(Vaccination)

DOI 10.1016/j.vaccine.2018.12.066

PMID 30665774

发布时间 2020-07-01

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