Daunorubicin oral bioavailability enhancement by surface coated natural biodegradable macromolecule chitosan based polymeric nanoparticles.

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第一作者： Niyaz,Ahmad

第一单位： Department of Pharmaceutics, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; Department of Pharmaceutical Chemistry, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia. Electronic address: nanhussain@iau.edu.sa.

作者： Niyaz,Ahmad ^[1] ; Rizwan,Ahmad ^[2] ; Md Aftab,Alam ^[3] ; Farhan Jalees,Ahmad ^[4] ; Mohd,Amir ^[2] ; Faheem Hyder,Pottoo ^[5] ; Md,Sarafroz ^[6] ; Mohammed,Jafar ^[7] ; Khalid,Umar ^[8]

作者单位： Department of Pharmaceutics, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; Department of Pharmaceutical Chemistry, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia. Electronic address: nanhussain@iau.edu.sa. ^[1] Department of Natural Products and Alternative Medicine, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia. ^[2] Department of Pharmaceutics, School of Medical and Allied Sciences, Galgotias University, Gautam Budh Nagar, Greater Noida 201310, India. ^[3] Nanomedicine Lab, Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, Hamdard Nagar, New Delhi, India. ^[4] Department of Pharmacology, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia. ^[5] Department of Pharmaceutical Chemistry, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia. ^[6] Department of Pharmaceutics, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia. ^[7] School of Chemical Sciences, Universiti Sains Malaysia, 11800 Pulau Pinang, Malaysia. ^[8]

关键词 Biodegradable polymers DAUN–NPs Daunorubicin In vitro cell line studies Pharmacokinetic analysis anticancer activity