Reduction of the expression of the late-onset Alzheimer's disease (AD) risk-factor <i>BIN1</i> does not affect amyloid pathology in an AD mouse model.
作者:
主题词
衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);阿尔茨海默病(Alzheimer Disease);淀粉样前体蛋白分泌酶类(Amyloid Precursor Protein Secretases);淀粉样β肽类(Amyloid beta-Peptides);淀粉样β蛋白前体(Amyloid beta-Protein Precursor);动物(Animals);天冬氨酸内肽酶类(Aspartic Acid Endopeptidases);脑(Brain);疾病模型, 动物(Disease Models, Animal);胞吞作用(Endocytosis);内颗粒(Endosomes);女(雌)性(Female);疾病遗传易感性(Genetic Predisposition to Disease);人类(Humans);男(雄)性(Male);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);神经组织蛋白质类(Nerve Tissue Proteins);肿瘤抑制蛋白质类(Tumor Suppressor Proteins)
DOI
10.1074/jbc.RA118.006379
PMID
30692199
发布时间
2021-02-05
- 浏览13

The Journal of biological chemistry
4477-4487页
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