IMP2 Increases Mouse Skeletal Muscle Mass and Voluntary Activity by Enhancing Autocrine Insulin-Like Growth Factor 2 Production and Optimizing Muscle Metabolism.-论文-万方医学网

作者： Laura,Regué ^[1] ; Fei,Ji ^[2] ; Daniel,Flicker ^[3] ; Dana,Kramer ^[1] ; William,Pierce ^[4] ; Teekhon,Davidoff ^[1] ; Jeffrey J,Widrick ^[5] ; Nicholas,Houstis ^[6] ; Liliana,Minichiello ^[1] ; Ning,Dai ^[1] ; Joseph,Avruch ^[7]

作者单位： Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, USA. ^[1] Diabetes Unit of the Medical Services, Massachusetts General Hospital, Boston, Massachusetts, USA. ^[2] Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA. ^[3] Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA. ^[4] Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA. ^[5] European Molecular Biology Laboratory, Mouse Biology Unit, Monterotondo, Italy. ^[6] Division of Genetics and Genomics, The Manton Center for Orphan Disease Research, Boston Children's Hospital, Boston, Massachusetts, USA. ^[7] Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA. ^[8] Cardiac Unit of the Medical Services, Massachusetts General Hospital, Boston, Massachusetts, USA. ^[9] Department of Pharmacology, University of Oxford, Oxford, United Kingdom. ^[10] Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, USA ning@molbio.mgh.harvard.edu avruch@molbio.mgh.harvard.edu. ^[11]

主题词动物(Animals);自身分泌性细胞间通讯(Autocrine Communication);脂肪酸类(Fatty Acids);女(雌)性(Female);葡萄糖(Glucose);糖原合成酶激酶3(Glycogen Synthase Kinase 3);胰岛素(Insulin);胰岛素样生长因子Ⅱ(Insulin-Like Growth Factor II);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);运动活动(Motor Activity);肌纤维, 骨骼(Muscle Fibers, Skeletal);肌, 骨骼(Muscle, Skeletal);PPARα(PPAR alpha);磷酰化(Phosphorylation);强体力活动(Physical Exertion);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);RNA结合蛋白质类(RNA-Binding Proteins);信号传导(Signal Transduction)

DOI 10.1128/MCB.00528-18

PMID 30692269

发布时间 2020-05-20

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IMP2 Increases Mouse Skeletal Muscle Mass and Voluntary Activity by Enhancing Autocrine Insulin-Like Growth Factor 2 Production and Optimizing Muscle Metabolism.

Molecular and cellular biology

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Molecular and cellular biology

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IMP2 Increases Mouse Skeletal Muscle Mass and Voluntary Activity by Enhancing Autocrine Insulin-Like Growth Factor 2 Production and Optimizing Muscle Metabolism.

Molecular and cellular biology

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Molecular and cellular biology

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