Neutralization of interleukin-9 ameliorates experimental stroke by repairing the blood-brain barrier via down-regulation of astrocyte-derived vascular endothelial growth factor-A.

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第一作者： Sha,Tan

第一单位： Department of Neurology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

作者： Sha,Tan ^[1] ; Yilong,Shan ^[1] ; Yinyao,Lin ^[1] ; Siyuan,Liao ^[1] ; Bingjun,Zhang ^[1] ; Qin,Zeng ^[1] ; Yuge,Wang ^[1] ; Zhezhi,Deng ^[1] ; Chen,Chen ^[1] ; Xueqiang,Hu ^[1] ; Lisheng,Peng ^[1] ; Wei,Qiu ^[1] ; Zhengqi,Lu ^[1]

作者单位： Department of Neurology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. ^[1]

关键词 BBB IL-9 ischemic stroke

主题词动物(Animals);抗体, 中和(Antibodies, Neutralizing);星形细胞(Astrocytes);血脑屏障(Blood-Brain Barrier);细胞低氧(Cell Hypoxia);细胞, 培养的(Cells, Cultured);纹状体(Corpus Striatum);培养基, 条件性(Culture Media, Conditioned);内皮, 血管(Endothelium, Vascular);葡萄糖(Glucose);缺氧缺血, 脑(Hypoxia-Ischemia, Brain);梗死, 大脑中动脉(Infarction, Middle Cerebral Artery);炎症(Inflammation);白细胞介素9(Interleukin-9);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);氧(Oxygen);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);重组蛋白质类(Recombinant Proteins);STAT3转录因子(STAT3 Transcription Factor);信号传导(Signal Transduction);增量调节(Up-Regulation);血管内皮生长因子A(Vascular Endothelial Growth Factor A)

DOI 10.1096/fj.201801595RR

PMID 30694693

发布时间 2020-05-11

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FASEB journal

2019年33卷3期

4376-4387页

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Neutralization of interleukin-9 ameliorates experimental stroke by repairing the blood-brain barrier via down-regulation of astrocyte-derived vascular endothelial growth factor-A.

FASEB journal

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FASEB journal

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Neutralization of interleukin-9 ameliorates experimental stroke by repairing the blood-brain barrier via down-regulation of astrocyte-derived vascular endothelial growth factor-A.

FASEB journal

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FASEB journal

相关期刊

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