The combination of ascorbate and menadione causes cancer cell death by oxidative stress and replicative stress.
作者:
主题词
抗坏血酸(Ascorbic Acid);细胞死亡(Cell Death);DNA复制(DNA Replication);复方合剂(Drug Combinations);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);谷氧还蛋白质类(Glutaredoxins);谷胱甘肽(Glutathione);人类(Humans);肿瘤(Neoplasms);孤儿核受体(Orphan Nuclear Receptors);氧化性应激(Oxidative Stress);活性氧(Reactive Oxygen Species);硫氧还蛋白质类(Thioredoxins);肿瘤细胞, 培养的(Tumor Cells, Cultured);维生素K3(Vitamin K 3);维生素类(Vitamins)
DOI
10.1016/j.freeradbiomed.2019.01.037
PMID
30703479
发布时间
2020-04-21
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Free radical biology & medicine
350-358页
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