Microglia pre-activation and neurodegeneration precipitate neuroinflammation without exacerbating tissue injury in experimental autoimmune encephalomyelitis.

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第一作者： Isabella,Wimmer

第一单位： Department of Neuroimmunology, Center for Brain Research, Medical University of Vienna, Spitalgasse 4, 1090, Vienna, Austria. isabella.wimmer@meduniwien.ac.at.

作者： Isabella,Wimmer ^[1] ; Cornelia,Scharler ^[2] ; Tobias,Zrzavy ^[2] ; Taro,Kadowaki ^[3] ; Verena,Mödlagl ^[2] ; Kim,Rojc ^[2] ; Anna R,Tröscher ^[2] ; Maja,Kitic ^[2] ; Shuichi,Ueda ^[4] ; Monika,Bradl ^[2] ; Hans,Lassmann ^[2]

作者单位： Department of Neuroimmunology, Center for Brain Research, Medical University of Vienna, Spitalgasse 4, 1090, Vienna, Austria. isabella.wimmer@meduniwien.ac.at. ^[1] Department of Neuroimmunology, Center for Brain Research, Medical University of Vienna, Spitalgasse 4, 1090, Vienna, Austria. ^[2] Department of Neuroimmunology, Center for Brain Research, Medical University of Vienna, Spitalgasse 4, 1090, Vienna, Austria.;Department of Neurology, Dokkyo Medical University, Tochigi, Japan. ^[3] Department of Histology and Neurobiology, Dokkyo Medical University, Tochigi, Japan. ^[4]

关键词 Experimental autoimmune encephalitis Microglia Neurodegeneration Progressive multiple sclerosis Zitter rat

主题词动物(Animals);动物, 异种(Animals, Outbred Strains);轴突(Axons);脑(Brain);疾病模型, 动物(Disease Models, Animal);脑炎(Encephalitis);脑脊髓炎, 自身免疫性, 实验性(Encephalomyelitis, Autoimmune, Experimental);人类(Humans);铁(Iron);男(雄)性(Male);小神经胶质细胞(Microglia);髓鞘(Myelin Sheath);大鼠, 近交Lew(Rats, Inbred Lew);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);T淋巴细胞(T-Lymphocytes)

DOI 10.1186/s40478-019-0667-9

PMID 30704526

发布时间 2020-04-02

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Acta neuropathologica communications

2019年7卷1期

14页

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Microglia pre-activation and neurodegeneration precipitate neuroinflammation without exacerbating tissue injury in experimental autoimmune encephalomyelitis.

Acta neuropathologica communications

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Acta neuropathologica communications

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Microglia pre-activation and neurodegeneration precipitate neuroinflammation without exacerbating tissue injury in experimental autoimmune encephalomyelitis.

Acta neuropathologica communications

相似文献

Acta neuropathologica communications

相关期刊

检索历史清除