Conformational Dynamics of Damage Processing by Human DNA Glycosylase NEIL1.

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第一作者： Olga A,Kladova

第一单位： SB RAS Institute of Chemical Biology and Fundamental Medicine, 8 Lavrentieva Ave., Novosibirsk 630090, Russia; Novosibirsk State University, 2 Pirogova St., Novosibirsk 630090, Russia. Electronic address: kladova@niboch.nsc.ru.

作者： Olga A,Kladova ^[1] ; Inga R,Grin ^[2] ; Olga S,Fedorova ^[3] ; Nikita A,Kuznetsov ^[4] ; Dmitry O,Zharkov ^[5]

作者单位： SB RAS Institute of Chemical Biology and Fundamental Medicine, 8 Lavrentieva Ave., Novosibirsk 630090, Russia; Novosibirsk State University, 2 Pirogova St., Novosibirsk 630090, Russia. Electronic address: kladova@niboch.nsc.ru. ^[1] SB RAS Institute of Chemical Biology and Fundamental Medicine, 8 Lavrentieva Ave., Novosibirsk 630090, Russia; Novosibirsk State University, 2 Pirogova St., Novosibirsk 630090, Russia. Electronic address: grin@niboch.nsc.ru. ^[2] SB RAS Institute of Chemical Biology and Fundamental Medicine, 8 Lavrentieva Ave., Novosibirsk 630090, Russia; Novosibirsk State University, 2 Pirogova St., Novosibirsk 630090, Russia. Electronic address: fedorova@niboch.nsc.ru. ^[3] SB RAS Institute of Chemical Biology and Fundamental Medicine, 8 Lavrentieva Ave., Novosibirsk 630090, Russia; Novosibirsk State University, 2 Pirogova St., Novosibirsk 630090, Russia. Electronic address: nikita.kuznetsov@niboch.nsc.ru. ^[4] SB RAS Institute of Chemical Biology and Fundamental Medicine, 8 Lavrentieva Ave., Novosibirsk 630090, Russia; Novosibirsk State University, 2 Pirogova St., Novosibirsk 630090, Russia. Electronic address: dzharkov@niboch.nsc.ru. ^[5]

关键词 DNA glycosylase DNA repair NEIL1 stopped-flow kinetics substrate recognition