首页> Oncoimmunology> Commentary: preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma by Garg <i>et al</i>. (2017).

Commentary: preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma by Garg <i>et al</i>. (2017).

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第一作者： Lijie,Zhai

第一单位： Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

作者： Lijie,Zhai ^[1] ; Erik,Ladomersky ^[1] ; Kristen L,Lauing ^[1] ; Meijing,Wu ^[1] ; Denise M,Scholtens ^[2] ; Rohan,Savoor ^[1] ; Bin,Zhang ^[3] ; Jennifer D,Wu ^[4] ; Craig,Horbinski ^[5] ; Rimas V,Lukas ^[6] ; David C,Binder ^[7] ; Derek A,Wainwright ^[8]

作者单位： Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. ^[1] Department of Preventive Medicine-Biostatistics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. ^[2] Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.;Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.;Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. ^[3] Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.;Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. ^[4] Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.;Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. ^[5] Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. ^[6] Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, CO, USA. ^[7] Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.;Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.;Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.;Department of Medicine-Division of Hematology and Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. ^[8]

关键词 IDO Treg brain tumor glioblastoma immunosuppression immunotherapy

医学主题词胶质母细胞瘤(Glioblastoma);人类(Humans);吲哚胺-吡咯2,3-双加氧酶(Indoleamine-Pyrrole 2,3,-Dioxygenase)

DOI 10.1080/2162402X.2018.1548242

PMID 30723577

发布时间 2022-03-05

基金项目

F32 NS073366/NS/NINDS NIH HHS/United States R00 NS082381/NS/NINDS NIH HHS/United States R01 CA204021/CA/NCI NIH HHS/United States R01 NS097851/NS/NINDS NIH HHS/United States T32 CA070085/CA/NCI NIH HHS/United States R01 CA208246/CA/NCI NIH HHS/United States K99 NS082381/NS/NINDS NIH HHS/United States

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