作者:
Kim,Vriens [1]
;
Stefan,Christen [2]
;
Sweta,Parik [1]
;
Dorien,Broekaert [2]
;
Kazuaki,Yoshinaga [1]
;
Ali,Talebi [2]
;
Jonas,Dehairs [3]
;
Carmen,Escalona-Noguero [4]
;
Roberta,Schmieder [1]
;
Thomas,Cornfield [2]
;
Catriona,Charlton [5]
;
Laura,Romero-Pérez [6]
;
Matteo,Rossi [7]
;
Gianmarco,Rinaldi [7]
;
Martin F,Orth [1]
;
Ruben,Boon [2]
;
Axelle,Kerstens [1]
;
Suet Ying,Kwan [2]
;
Brandon,Faubert [8]
;
Andrés,Méndez-Lucas [8]
;
Charlotte C,Kopitz [9]
;
Ting,Chen [1]
;
Juan,Fernandez-Garcia [2]
;
João A G,Duarte [1]
;
Arndt A,Schmitz [2]
;
Patrick,Steigemann [9]
;
Mustapha,Najimi [10]
;
Andrea,Hägebarth [11]
;
Jo A,Van Ginderachter [12]
;
Etienne,Sokal [13]
;
Naohiro,Gotoh [14]
;
Kwok-Kin,Wong [15]
;
Catherine,Verfaillie [16]
;
Rita,Derua [17]
;
Sebastian,Munck [1]
;
Mariia,Yuneva [2]
;
Laura,Beretta [1]
;
Ralph J,DeBerardinis [2]
;
Johannes V,Swinnen [16]
;
Leanne,Hodson [16]
;
David,Cassiman [18]
;
Chris,Verslype [16]
;
Sven,Christian [3]
;
Sylvia,Grünewald [4]
;
Thomas G P,Grünewald [18]
;
Sarah-Maria,Fendt [19]
作者单位:
Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, VIB, Leuven, Belgium.
[1]
Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium.
[2]
Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium.
[3]
Myeloid Cell Immunology Laboratory, VIB Center for Inflammation Research, Brussels, Belgium.
[4]
Tsukishima Foods Industry, Tokyo, Japan.
[5]
Cluster of Agricultural Sciences, Faculty of Food and Agricultural Sciences, Fukushima University, Fukushima, Japan.
[6]
Laboratory of Lipid Metabolism and Cancer, Department of Oncology, Leuven Cancer Institute (LKI), Leuven, Belgium.
[7]
The Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Churchill Hospital, Oxford, UK.
[8]
Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
[9]
Stem Cell Institute, Department of Development and Regeneration, KU Leuven, Leuven, Belgium.
[10]
VIB Bio Imaging Core and VIB-KU Leuven Center for Brain & Disease Research, KU Leuven, Leuven, Belgium.
[11]
Molecular Neurobiology, Department of Neuroscience, KU Leuven, Leuven, Belgium.
[12]
Department of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
[13]
Children's Medical Center Research Institute, UT Southwestern, Dallas, TX, USA.
[14]
The Francis Crick Institute, London, UK.
[15]
Bayer AG, Research & Development, Pharmaceuticals, Berlin, Germany.
[16]
Perlmutter Cancer Center, NYU Langone Medical Center, Smilow Research Center, New York, NY, USA.
[17]
Laboratory of Pediatric Hepatology and Cell Therapy, Institut de Recherche Expérimentale et Clinique (IREC), Université Catholique de Louvain and Cliniques Universitaires St Luc, Brussels, Belgium.
[18]
Department of Food Science and Technology, Tokyo University of Marine Science and Technology, Tokyo, Japan.
[19]
Laboratory of Protein Phosphorylation and Proteomics, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
[20]
Howard Hughes Medical Institute, UT Southwestern Medical Center, Dallas, TX, USA.
[21]
Department of Hepatology, KU Leuven, Leuven, Belgium.
[22]
Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium.
[23]
Department of Digestive Oncology, KU Leuven, Leuven, Belgium.
[24]
Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
[25]
German Cancer Consortium (DKTK), Partner site Munich, Munich, Germany.
[26]
German Cancer Research Center (DKFZ), Heidelberg, Germany.
[27]
Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, VIB, Leuven, Belgium. sarah-maria.fendt@kuleuven.vib.be.
[28]
Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium. sarah-maria.fendt@kuleuven.vib.be.
[29]
主题词
动物(Animals);细胞系, 肿瘤(Cell Line, Tumor);细胞膜(Cell Membrane);细胞增殖(Cell Proliferation);脂肪酸去饱和酶类(Fatty Acid Desaturases);脂肪酸类(Fatty Acids);女(雌)性(Female);HEK293细胞(HEK293 Cells);人类(Humans);男(雄)性(Male);代谢网络和途径(Metabolic Networks and Pathways);小鼠(Mice);肿瘤(Neoplasms);油酸类(Oleic Acids);棕榈酸盐类(Palmitates);棕榈酸类(Palmitic Acids);硬脂酰CoA去饱和酶(Stearoyl-CoA Desaturase)
DOI
10.1038/s41586-019-0904-1
PMID
30728499
发布时间
2022-02-23
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Nature
Nature
403-406页
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