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首页> Carbohydrate polymers> Long-term local PDGF delivery using porous microspheres modified with heparin for tendon healing of rotator cuff tendinitis in a rabbit model.

Long-term local PDGF delivery using porous microspheres modified with heparin for tendon healing of rotator cuff tendinitis in a rabbit model.

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作者： Seok,Kang ^[1] ; Joon Shik,Yoon ^[1] ; Jae Yong,Lee ^[2] ; Hak-Jun,Kim ^[3] ; Kyeongsoon,Park ^[4] ; Sung Eun,Kim ^[5]

作者单位： Department of Physical Medicine and Rehabilitation, Korea University Guro Hospital, 148, Gurodong-ro, Guro-gu, Seoul, 08308, South Korea. ^[1] Department of Biomedical Science, Korea University Medical College, Korea University, Anam-dong, Seongbuk-gu, 02841, South Korea. ^[2] Department of Orthopedic Surgery and Rare Diseases Institute, Korea University Guro Hospital, 148, Gurodong-ro, Guro-gu, Seoul, 08308, South Korea. ^[3] Department of Systems Biotechnology, Chung-Ang University, Anseong-si, Gyeonggi-do, 17546, South Korea. Electronic address: kspark1223@cau.ac.kr. ^[4] Department of Orthopedic Surgery and Rare Diseases Institute, Korea University Guro Hospital, 148, Gurodong-ro, Guro-gu, Seoul, 08308, South Korea. Electronic address: sekim10@korea.ac.kr. ^[5]

关键词 2-(N-morpholino)-ethanesulfonic acid (Pubchem CID:4478249)Anti-inflammation Dichloromethane (DCM) (PubChem CID: 6344)Dimethylsulfoxide (DMSO) (PubChem CID: 679)Dopamine hydrochloride (PubChem CID:65340)Heparin Heparin sodium (PubChem CID:22833565)PDGF Poly (lactic-co-glycolic acid) (PLGA) (Pubchem CID: 23111554)Polyvinyl alcohol (PVA) (PubChem CID: 11199)Porous microspheres Recombinant human PDGF (PubChem SID: 135290697)Rotator cuff tendinitis Sodium chloride (PubChem CID:5234)Tendon healing Thiazolyl blue tetrazolium bromide (MTT) (PubChem CID:64965)

主题词动物(Animals);细胞增殖(Cell Proliferation);疾病模型, 动物(Disease Models, Animal);多巴胺(Dopamine);药物载体(Drug Carriers);肝素(Heparin);微球体(Microspheres);血小板源性生长因子(Platelet-Derived Growth Factor);多孔性(Porosity);兔(Rabbits);表面特性(Surface Properties);腱(Tendons);时间因素(Time Factors)

DOI 10.1016/j.carbpol.2019.01.017

PMID 30732820

发布时间 2019-05-24

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