A Novel Anti-EGFR mAb Ame55 with Lower Toxicity and Better Efficacy than Cetuximab When Combined with Irinotecan.

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作者： Weiyi,Qiu ^[1] ; Chang,Zhang ^[1] ; Shuang,Wang ^[2] ; Xiaoyan,Yu ^[1] ; Qiong,Wang ^[1] ; Dadi,Zeng ^[1] ; Peng,Du ^[1] ; Jinling,Ma ^[1] ; Yiqiong,Zheng ^[3] ; Bo,Pang ^[4] ; Yunzhou,Yu ^[5] ; Feng,Long ^[1] ; Xiaobin,Pang ^[1] ; Zhiwei,Sun ^[2]

作者单位： Antibody Engineering Group, Beijing Biotechnology Institute, 100071 Beijing, China. ^[1] Pharmaceutical Institute, Henan University, 475004 Kaifeng, China. ^[2] Joinn Laboratories (China), Co. Ltd, 100176 Beijing, China. ^[3] 301 Hospital, 100853 Beijing, China. ^[4] Clinical Laboratory, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, 100053 Beijing, China. ^[5]

主题词动物(Animals);抗体, 单克隆(Antibodies, Monoclonal);抗体亲和力(Antibody Affinity);抗肿瘤联合化疗方案(Antineoplastic Combined Chemotherapy Protocols);CHO细胞(CHO Cells);细胞系, 肿瘤(Cell Line, Tumor);结肠肿瘤(Colonic Neoplasms);仓鼠属(Cricetulus);药物协同作用(Drug Synergism);女(雌)性(Female);人类(Humans);成束猴(Macaca fascicularis);男(雄)性(Male);小鼠, 裸(Mice, Nude);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)

DOI 10.1155/2019/3017360

PMID 30733972

发布时间 2020-02-25

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Journal of immunology research

2019年2019卷

3017360页

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A Novel Anti-EGFR mAb Ame55 with Lower Toxicity and Better Efficacy than Cetuximab When Combined with Irinotecan.

Journal of immunology research

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Journal of immunology research

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A Novel Anti-EGFR mAb Ame55 with Lower Toxicity and Better Efficacy than Cetuximab When Combined with Irinotecan.

Journal of immunology research

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Journal of immunology research

相关期刊

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