Multifactorial heterogeneity of virus-specific T cells and association with the progression of human chronic hepatitis B infection.

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作者： Yang,Cheng ^[1] ; Yuan O,Zhu ^[2] ; Etienne,Becht ^[1] ; Pauline,Aw ^[2] ; Jinmiao,Chen ^[1] ; Michael,Poidinger ^[1] ; Paola Flórez,de Sessions ^[2] ; Martin Lloyd,Hibberd ^[2] ; Antonio,Bertoletti ^[3] ; Seng Gee,Lim ^[1] ; Evan W,Newell ^[4]

作者单位： Singapore Immunology Network, Agency for Science, Technology and Research, Singapore. ^[1] Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore. ^[2] Emerging Infectious Disease, Department of Pathogen Molecular Biology, London School of Hygiene & Tropical Medicine, London, UK. ^[3] Emerging Infectious Disease Program, Duke-NUS Medical School, Singapore. ^[4] Division of Gastroenterology & Hepatology, National University Health System, Singapore. ^[5] Singapore Immunology Network, Agency for Science, Technology and Research, Singapore. enewell@fredhutch.org. ^[6] Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. ^[7]

主题词成年人(Adult);老年人(Aged);抗病毒药(Antiviral Agents);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);儿童(Child);DNA, 病毒(DNA, Viral);疾病恶化(Disease Progression);表位, T淋巴细胞(Epitopes, T-Lymphocyte);女(雌)性(Female);HLA-A抗原(HLA-A Antigens);乙型肝炎病毒(Hepatitis B virus);乙型肝炎, 慢性(Hepatitis B, Chronic);人类(Humans);纵向研究(Longitudinal Studies);男(雄)性(Male);中年人(Middle Aged);表型(Phenotype);受体, 抗原, T细胞(Receptors, Antigen, T-Cell);青年人(Young Adult)

DOI 10.1126/sciimmunol.aau6905

PMID 30737354

发布时间 2020-04-08

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Science immunology

2019年4卷32期

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Multifactorial heterogeneity of virus-specific T cells and association with the progression of human chronic hepatitis B infection.

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Multifactorial heterogeneity of virus-specific T cells and association with the progression of human chronic hepatitis B infection.

Science immunology

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Science immunology

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