换一批
换一批Brain permeant and impermeant inhibitors of fatty-acid amide hydrolase suppress the development and maintenance of paclitaxel-induced neuropathic pain without producing tolerance or physical dependence in vivo and synergize with paclitaxel to reduce tumor cell line viability in vitro.
第一作者：
Richard A,Slivicki
第一单位：
Program in Neuroscience, Indiana University, Bloomington, IN, United States; Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, United States.
作者：
主题词
酰胺基水解酶类(Amidohydrolases);镇痛药(Analgesics);动物(Animals);抗肿瘤药(Antineoplastic Agents);苯甲酰胺类(Benzamides);苯并恶嗪类(Benzoxazines);脑(Brain);大麻酚类(Cannabinoids);氨甲酸酯类(Carbamates);细胞系, 肿瘤(Cell Line, Tumor);细胞存活(Cell Survival);药物协同作用(Drug Synergism);药物耐受性(Drug Tolerance);HEK293细胞(HEK293 Cells);人类(Humans);痛觉过敏(Hyperalgesia);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);吗啉类(Morpholines);萘类(Naphthalenes);神经痛(Neuralgia);紫杉酚(Paclitaxel);物质相关性障碍(Substance-Related Disorders)
DOI
10.1016/j.phrs.2019.02.002
PMID
30739035
发布时间
2021-02-23
- 浏览8
Pharmacological research
267-282页
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