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Assay development for determination of DZ2002, a new reversible SAHH inhibitor, and its acid metabolite DZA in blood and application to rat pharmacokinetic study.

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第一作者： Weiwei,Jia

第一单位： State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.

作者： Weiwei,Jia ^[1] ; Jing,Li ^[2] ; Feifei,Du ^[1] ; Yan,Sun ^[3] ; Fang,Xu ^[1] ; Fengqing,Wang ^[1] ; Olajide E,Olaleye ^[1] ; Danghui,Chen ^[1] ; Wei,Tang ^[1] ; Jianping,Zuo ^[1] ; Chuan,Li ^[2]

作者单位： State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. ^[1] State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.;University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100049, China. ^[2] Fudan University Shanghai Cancer Center, Shanghai 200032, China. ^[3]

关键词 Carboxylesterases DZ2002 Pharmacokinetics S-adenosyl-L-homocysteine hydrolase

DOI 10.1016/j.jpha.2018.09.001

PMID 30740254

发布时间 2020-09-30

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Journal of pharmaceutical analysis

2019年9卷1期

25-33页

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Journal of pharmaceutical analysis

2019年9卷1期

25-33页

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Assay development for determination of DZ2002, a new reversible SAHH inhibitor, and its acid metabolite DZA in blood and application to rat pharmacokinetic study.

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Assay development for determination of DZ2002, a new reversible SAHH inhibitor, and its acid metabolite DZA in blood and application to rat pharmacokinetic study.

Journal of pharmaceutical analysis

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Journal of pharmaceutical analysis

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