PD-L1 on invasive fibroblasts drives fibrosis in a humanized model of idiopathic pulmonary fibrosis.

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第一作者： Yan,Geng

第一单位： Department of Medicine, Division of Pulmonary and Critical Care Medicine, Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.

作者： Yan,Geng ^[1] ; Xue,Liu ^[2] ; Jiurong,Liang ^[1] ; David M,Habiel ^[1] ; Vrishika,Kulur ^[1] ; Ana Lucia,Coelho ^[1] ; Nan,Deng ^[1] ; Ting,Xie ^[3] ; Yizhou,Wang ^[1] ; Ningshan,Liu ^[4] ; Guanling,Huang ^[1] ; Adrianne,Kurkciyan ^[1] ; Zhenqiu,Liu ^[1] ; Jie,Tang ^[3] ; Cory M,Hogaboam ^[4] ; Dianhua,Jiang ^[1] ; Paul W,Noble ^[1]

作者单位： Department of Medicine, Division of Pulmonary and Critical Care Medicine, Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA. ^[1] School of Pharmaceutical Science, Jiangnan University, Wuxi, Jiangsu, China. ^[2] Biostatistics & Bioinformatics Core. ^[3] Genomics Core, and. ^[4] Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA. ^[5]

关键词 Cell migration/adhesion Fibrosis Pulmonology Respiration Therapeutics

主题词动物(Animals);细胞黏附(Cell Adhesion);女(雌)性(Female);成纤维细胞(Fibroblasts);纤维化(Fibrosis);人类(Humans);特发性肺纤维化(Idiopathic Pulmonary Fibrosis);肺(Lung);小鼠(Mice);小鼠, 近交NOD(Mice, Inbred NOD);小鼠, 基因敲除(Mice, Knockout);小鼠, SCID(Mice, SCID);表型(Phenotype)

DOI 10.1172/jci.insight.125326

PMID 30763282

发布时间 2020-06-22

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PD-L1 on invasive fibroblasts drives fibrosis in a humanized model of idiopathic pulmonary fibrosis.

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PD-L1 on invasive fibroblasts drives fibrosis in a humanized model of idiopathic pulmonary fibrosis.

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