Systemic translocation of Staphylococcus drives autoantibody production in HIV disease.

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第一作者： Zhenwu,Luo

第一单位： Department of Microbiology and Immunology, Medical University of South Carolina, 173 Ashley Ave. BSB208D, Charleston, SC, 29425, USA.

作者： Zhenwu,Luo ^[1] ; Min,Li ^[1] ; Yongxia,Wu ^[1] ; Zhefeng,Meng ^[2] ; Lisa,Martin ^[3] ; Lumin,Zhang ^[4] ; Elizabeth,Ogunrinde ^[1] ; Zejun,Zhou ^[1] ; Shenghui,Qin ^[1] ; Zhuang,Wan ^[1] ; Maria Anna Julia,Westerink ^[1] ; Stephanie,Warth ^[3] ; Hui,Liu ^[5] ; Ping,Jin ^[5] ; David,Stroncek ^[5] ; Quan-Zhen,Li ^[6] ; Ena,Wang ^[7] ; Xueling,Wu ^[8] ; Sonya L,Heath ^[9] ; Zihai,Li ^[1] ; Alexander V,Alekseyenko ^[10] ; Wei,Jiang ^[11]

作者单位： Department of Microbiology and Immunology, Medical University of South Carolina, 173 Ashley Ave. BSB208D, Charleston, SC, 29425, USA. ^[1] Department of Gastroenterology, Oncology Bioinformatics Center, Minhang Hospital, Fudan University, Shanghai, China. ^[2] Division of Infectious Diseases, Department of Medicine, Medical University of South Carolina, Charleston, SC, 29425, USA. ^[3] Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. ^[4] Cell Processing Section (CPS), Department of Transfusion Medicine, Clinical Center, NIH, Bethesda, 20892, USA. ^[5] Department of Immunology and Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390, USA. ^[6] Sidra Medical and Research Center, Doha, Qatar. ^[7] Aaron Diamond AIDS Research Center, The Rockefeller University, New York, NY, 10016, USA. ^[8] Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, 35294, USA. ^[9] Program for Human Microbiome Research, Biomedical Informatics Center, Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC, 29425, USA. ^[10] Department of Microbiology and Immunology, Medical University of South Carolina, 173 Ashley Ave. BSB208D, Charleston, SC, 29425, USA. jianw@musc.edu. ^[11] Division of Infectious Diseases, Department of Medicine, Medical University of South Carolina, Charleston, SC, 29425, USA. jianw@musc.edu. ^[12]

关键词 Autoantibodies Plasma microbial 16S rDNA Staphylococcus

主题词动物(Animals);自身抗体(Autoantibodies);细菌移位(Bacterial Translocation);DNA, 细菌(DNA, Bacterial);DNA, 核糖体(DNA, Ribosomal);疾病模型, 动物(Disease Models, Animal);生发中心(Germinal Center);HIV感染(HIV Infections);Hep G2细胞(Hep G2 Cells);人类(Humans);免疫, 先天(Immunity, Innate);流感疫苗(Influenza Vaccines);流感, 人(Influenza, Human);淋巴细胞活化(Lymphocyte Activation);男(雄)性(Male);小鼠(Mice);单细胞分析(Single-Cell Analysis);葡萄球菌属(Staphylococcus);增量调节(Up-Regulation)

DOI 10.1186/s40168-019-0646-1

PMID 30764863

发布时间 2020-03-09

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Microbiome

2019年7卷1期

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Systemic translocation of Staphylococcus drives autoantibody production in HIV disease.

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Systemic translocation of Staphylococcus drives autoantibody production in HIV disease.

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