换一批
第一作者：
Qin,Shi
第一单位：
State Key Laboratory of Natural Medicines, Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
作者：
关键词
API, active pharmaceutical ingredient;AUC, area under plasma concentrations-time curveBCS, bio-pharmaceutics classification systemsBioavailabilityCharacterizationCmax, maximum plasma concentrationCoamorphousCss, plasma concentration at steady stateDSC, differential scanning calorimetryDVS, dynamic vapor sorptionDc, relative degree of crystallizationDissolutionFT-IR, fourier transform infrared spectroscopyHME, hot melt extrusionHPLC, high performance liquid chromatographyIDR, intrinsic dissolution rateLFRS, low-frequency Raman spectroscopyLLPS, liquid—liquid phase separationMTDSC, modulated temperature differential scanning calorimetryNMR, nuclear magnetic resonanceP-gp, P-glycoproteinPXRD, powder X-ray diffractionPhysical stabilityPreparationRH, relative humiditySEM, scanning electron microscopeTGA, thermogravimetric analysisTg, glass transition temperatureTmax, time of maximum plasma concentrationUV, ultraviolet spectroscopy
DOI
10.1016/j.apsb.2018.08.002
PMID
30766775
发布时间
2020-09-29
- 浏览9
Acta pharmaceutica Sinica. B
2019年9卷1期
19-35页
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