Accelerated bio-cognitive aging in Down syndrome: State of the art and possible deceleration strategies.

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第一作者： Claudio,Franceschi

第一单位： IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.

作者： Claudio,Franceschi ^[1] ; Paolo,Garagnani ^[2] ; Noémie,Gensous ^[3] ; Maria Giulia,Bacalini ^[4] ; Maria,Conte ^[5] ; Stefano,Salvioli ^[6]

作者单位： IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy. ^[1] Lobachevsky State University of Nizhny Novgorod, Nizhny Novgorod, Russia. ^[2] Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Bologna, Italy. ^[3] Clinical Chemistry, Department of Laboratory Medicine, Karolinska Institutet at Huddinge University Hospital, Stockholm, Sweden. ^[4] Applied Biomedical Research Center (CRBA), S. Orsola-Malpighi Polyclinic, Bologna, Italy. ^[5] CNR Institute of Molecular Genetics, Unit of Bologna, Bologna, Italy. ^[6] Interdepartmental Center "L. Galvani" (CIG), University of Bologna, Bologna, Italy. ^[7]

关键词 Down syndrome accelerated aging anti-aging strategies cognitive impairment metformin

主题词动物(Animals);唐氏综合征(Down Syndrome);人类(Humans)

DOI 10.1111/acel.12903

PMID 30768754

发布时间 2024-07-17

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