首页> Journal of Alzheimer's disease : JAD> Small Molecule Amyloid-β Protein Precursor Processing Modulators Lower Amyloid-β Peptide Levels via cKit Signaling.

Small Molecule Amyloid-β Protein Precursor Processing Modulators Lower Amyloid-β Peptide Levels via cKit Signaling.

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第一作者： Ci-Di,Chen

第一单位： Department of Biochemistry, Boston University School of Medicine, Boston, MA, USA.

作者： Ci-Di,Chen ^[1] ; Ella,Zeldich ^[1] ; Christina,Khodr ^[1] ; Kaddy,Camara ^[2] ; Tze Yu,Tung ^[3] ; Emma C,Lauder ^[4] ; Patrick,Mullen ^[1] ; Taryn J,Polanco ^[1] ; Yen-Yu,Liu ^[3] ; Dean,Zeldich ^[5] ; Weiming,Xia ^[6] ; William E,Van Nostrand ^[7] ; Lauren E,Brown ^[8] ; John A,Porco ^[2] ; Carmela R,Abraham ^[9]

作者单位： Department of Biochemistry, Boston University School of Medicine, Boston, MA, USA. ^[1] Department of Chemistry, Boston University, Boston, MA, USA.;Center for Molecular Discovery (BU-CMD), Boston University, Boston, MA, USA. ^[2] Department of Biology, Boston University, Boston, MA, USA. ^[3] Department of Neuroscience, Boston University, Boston, MA, USA. ^[4] Department of Biomedical Engineering, Boston University, Boston, MA, USA. ^[5] Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, MA, USA.;Bedford Geriatric Research Education Clinical Center, Bedford VA Medical Center, Bedford, MA, USA. ^[6] Department of Biomedical and Pharmaceutical Sciences, University of Rhode Island, Kingston, RI, USA. ^[7] Department of Chemistry, Boston University, Boston, MA, USA.;Center for Molecular Discovery (BU-CMD), Boston University, Boston, MA, USA.;Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, MA, USA. ^[8] Department of Biochemistry, Boston University School of Medicine, Boston, MA, USA.;Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, MA, USA. ^[9]

关键词 High throughput screening kinase neurodegeneration phosphatase phosphorylation