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Comprehensive and quantitative analysis of white and brown adipose tissue by shotgun lipidomics.

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第一作者： Michal,Grzybek

第一单位： Paul Langerhans Institute Dresden of the Helmholtz Zentrum Munich at the University Clinic Carl Gustav Carus, TU Dresden, Dresden, Germany; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.

作者： Michal,Grzybek ^[1] ; Alessandra,Palladini ^[1] ; Vasileia I,Alexaki ^[2] ; Michal A,Surma ^[3] ; Kai,Simons ^[3] ; Triantafyllos,Chavakis ^[4] ; Christian,Klose ^[5] ; Ünal,Coskun ^[6]

作者单位： Paul Langerhans Institute Dresden of the Helmholtz Zentrum Munich at the University Clinic Carl Gustav Carus, TU Dresden, Dresden, Germany; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany. ^[1] Institute for Clinical Chemistry and Laboratory Medicine, Faculty of Medicine, TU Dresden, Dresden, Germany. ^[2] Lipotype GmbH, Dresden, Germany. ^[3] Paul Langerhans Institute Dresden of the Helmholtz Zentrum Munich at the University Clinic Carl Gustav Carus, TU Dresden, Dresden, Germany; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany; Institute for Clinical Chemistry and Laboratory Medicine, Faculty of Medicine, TU Dresden, Dresden, Germany. ^[4] Lipotype GmbH, Dresden, Germany. Electronic address: klose@lipotype.de. ^[5] Paul Langerhans Institute Dresden of the Helmholtz Zentrum Munich at the University Clinic Carl Gustav Carus, TU Dresden, Dresden, Germany; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany. Electronic address: coskun@plid.de. ^[6]

关键词 Adipose tissue Chow and high-fat diet Lipid extraction Lipid remodeling Lipidomics Method validation Mouse Shotgun mass spectrometry

医学主题词脂肪组织, 棕色(Adipose Tissue, Brown);脂肪组织, 白色(Adipose Tissue, White);动物(Animals);女(雌)性(Female);脂类(Lipids);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL)

DOI 10.1016/j.molmet.2019.01.009

PMID 30777728

发布时间 2020-04-13

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