首页> Nature communications> Intradermal delivery of modified mRNA encoding VEGF-A in patients with type 2 diabetes.

Intradermal delivery of modified mRNA encoding VEGF-A in patients with type 2 diabetes.

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第一作者： Li-Ming,Gan

第一单位： Early Clinical Development, IMED Biotech Unit, AstraZeneca Gothenburg, Pepparedsleden 1, 431 50, Mölndal, Sweden. li-ming.gan@astrazeneca.com.;Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Arvid Wallgrens backe 1, 413 46, Gothenburg, Sweden. li-ming.gan@astrazeneca.com.;Department of Cardiology, Sahlgrenska University Hospital, Blå stråket 5, 413 45, Gothenburg, Sweden. li-ming.gan@astrazeneca.com.

作者： Li-Ming,Gan ^[1] ; Maria,Lagerström-Fermér ^[2] ; Leif G,Carlsson ^[3] ; Cecilia,Arfvidsson ^[2] ; Ann-Charlotte,Egnell ^[2] ; Anna,Rudvik ^[2] ; Magnus,Kjaer ^[2] ; Anna,Collén ^[3] ; James D,Thompson ^[4] ; John,Joyal ^[4] ; Ligia,Chialda ^[5] ; Thomas,Koernicke ^[5] ; Rainard,Fuhr ^[5] ; Kenneth R,Chien ^[6] ; Regina,Fritsche-Danielson ^[3]

作者单位： Early Clinical Development, IMED Biotech Unit, AstraZeneca Gothenburg, Pepparedsleden 1, 431 50, Mölndal, Sweden. li-ming.gan@astrazeneca.com.;Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Arvid Wallgrens backe 1, 413 46, Gothenburg, Sweden. li-ming.gan@astrazeneca.com.;Department of Cardiology, Sahlgrenska University Hospital, Blå stråket 5, 413 45, Gothenburg, Sweden. li-ming.gan@astrazeneca.com. ^[1] Early Clinical Development, IMED Biotech Unit, AstraZeneca Gothenburg, Pepparedsleden 1, 431 50, Mölndal, Sweden. ^[2] Cardiovascular, Renal and Metabolism IMED Biotech Unit, AstraZeneca Gothenburg, Pepparedsleden 1, 431 50, Mölndal, Sweden. ^[3] Moderna, Inc., 200 Technology Square, Cambridge, MA, 02139, USA. ^[4] PAREXEL Early Phase Clinical Unit, Westend Clinic, House 31, 14050, Berlin, Germany. ^[5] Department of Cell and Molecular Biology, Karolinska Institutet, 171 77, Stockholm, Sweden.;Integrated Cardio Metabolic Center, Karolinska Institutet, Blickagången 6, SE-141 57, Huddinge, Sweden. ^[6]