Regulation of c-Raf Stability through the CTLH Complex.

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第一作者： Christina J,McTavish

第一单位： Robarts Research Institute, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, ON N6A 5B7, Canada. christina.mctavish@gmail.com.

作者： Christina J,McTavish ^[1] ; Wesley,Bérubé-Janzen ^[2] ; Xu,Wang ^[3] ; Matthew E R,Maitland ^[4] ; Louisa M,Salemi ^[5] ; David A,Hess ^[6] ; Caroline,Schild-Poulter ^[7]

作者单位： Robarts Research Institute, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, ON N6A 5B7, Canada. christina.mctavish@gmail.com. ^[1] Department of Biochemistry, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, ON N6A 5C1, Canada. christina.mctavish@gmail.com. ^[2] Robarts Research Institute, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, ON N6A 5B7, Canada. wesleyjanzen@hotmail.com. ^[3] Department of Biochemistry, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, ON N6A 5C1, Canada. wesleyjanzen@hotmail.com. ^[4] Robarts Research Institute, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, ON N6A 5B7, Canada. xwang287@uwo.ca. ^[5] Robarts Research Institute, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, ON N6A 5B7, Canada. mmaitla2@uwo.ca. ^[6] Department of Biochemistry, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, ON N6A 5C1, Canada. mmaitla2@uwo.ca. ^[7] Robarts Research Institute, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, ON N6A 5B7, Canada. louisa.salemi@gmail.com. ^[8] Department of Biochemistry, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, ON N6A 5C1, Canada. louisa.salemi@gmail.com. ^[9] Robarts Research Institute, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, ON N6A 5B7, Canada. dhess@robarts.ca. ^[10] Department of Physiology and Pharmacology, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, ON N6A 5C1, Canada. dhess@robarts.ca. ^[11] Robarts Research Institute, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, ON N6A 5B7, Canada. cschild-poulter@robarts.ca. ^[12] Department of Biochemistry, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, ON N6A 5C1, Canada. cschild-poulter@robarts.ca. ^[13]

关键词 CTLH complex ERK pathway RMND5A RanBPM c-Raf cancer ubiquitination