Targeting an RNA-Binding Protein Network in Acute Myeloid Leukemia.-论文-万方医学网

作者： Eric,Wang ^[1] ; Sydney X,Lu ^[2] ; Alessandro,Pastore ^[2] ; Xufeng,Chen ^[1] ; Jochen,Imig ^[1] ; Stanley,Chun-Wei Lee ^[2] ; Kathryn,Hockemeyer ^[1] ; Yohana E,Ghebrechristos ^[1] ; Akihide,Yoshimi ^[2] ; Daichi,Inoue ^[2] ; Michelle,Ki ^[2] ; Hana,Cho ^[2] ; Lillian,Bitner ^[2] ; Andreas,Kloetgen ^[1] ; Kuan-Ting,Lin ^[3] ; Taisuke,Uehara ^[4] ; Takashi,Owa ^[4] ; Raoul,Tibes ^[1] ; Adrian R,Krainer ^[3] ; Omar,Abdel-Wahab ^[5] ; Iannis,Aifantis ^[6]

作者单位： Department of Pathology and Laura & Isaac Perlmutter Cancer Center, NYU School of Medicine, New York, NY 10016, USA. ^[1] Human Oncology and Pathogenesis Program and Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. ^[2] Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA. ^[3] Tsukuba Research Laboratories, Eisai Company, Ltd, Tsukuba, Ibaraki 300-4352, Japan. ^[4] Human Oncology and Pathogenesis Program and Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address: abdelwao@mskcc.org. ^[5] Department of Pathology and Laura & Isaac Perlmutter Cancer Center, NYU School of Medicine, New York, NY 10016, USA. Electronic address: iannis.aifantis@nyumc.org. ^[6]

主题词选择性剪接(Alternative Splicing);动物(Animals);细胞系, 肿瘤(Cell Line, Tumor);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因调控网络(Gene Regulatory Networks);基因打靶(Gene Targeting);HL-60细胞(HL-60 Cells);同源盒结构域蛋白质类(Homeodomain Proteins);人类(Humans);Jurkat细胞(Jurkat Cells);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);男(雄)性(Male);小鼠(Mice);肿瘤移植(Neoplasm Transplantation);预后(Prognosis);蛋白质组学(Proteomics);RNA结合蛋白质类(RNA-Binding Proteins);序列分析, RNA(Sequence Analysis, RNA);存活率分析(Survival Analysis);增量调节(Up-Regulation)

DOI 10.1016/j.ccell.2019.01.010

PMID 30799057

发布时间 2022-01-19

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Targeting an RNA-Binding Protein Network in Acute Myeloid Leukemia.

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Targeting an RNA-Binding Protein Network in Acute Myeloid Leukemia.

Cancer cell

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Cancer cell

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