The serotonin-2C agonist Lorcaserin delays intravenous choice and modifies the subjective and cardiovascular effects of cocaine: A randomized, controlled human laboratory study.

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作者： Jimmie L,Pirtle ^[1] ; Melissa D,Hickman ^[1] ; Varun C,Boinpelly ^[1] ; Kamalakar,Surineni ^[2] ; Hemant K,Thakur ^[1] ; Kenneth W,Grasing ^[3]

作者单位： Substance Abuse Research Laboratory, Kansas City Veterans Affairs Medical Center, 4801 Linwood Boulevard, Kansas City, MO 64128, United States of America. ^[1] Substance Abuse Research Laboratory, Kansas City Veterans Affairs Medical Center, 4801 Linwood Boulevard, Kansas City, MO 64128, United States of America; Department of Psychiatry, University of Kansas School of Medicine, Wichita, KS 67226, United States of America. ^[2] Substance Abuse Research Laboratory, Kansas City Veterans Affairs Medical Center, 4801 Linwood Boulevard, Kansas City, MO 64128, United States of America; Division of Clinical Pharmacology, Department of Medicine, University of Kansas School of Medicine, Kansas City, KS 66160, United States of America. Electronic address: kgrasing@kumc.edu. ^[3]

主题词投药, 口服(Administration, Oral);成年人(Adult);苯丙氮|艹卓|类(Benzazepines);血压(Blood Pressure);可卡因(Cocaine);可卡因相关性障碍(Cocaine-Related Disorders);交叉研究(Cross-Over Studies);抑制, 化学性(Depression, Chemical);双盲法(Double-Blind Method);药物疗法, 联合(Drug Therapy, Combination);心率(Heart Rate);人类(Humans);男(雄)性(Male);中年人(Middle Aged);自我遵嘱服药(Self Administration);血清素5-HT2受体激动剂(Serotonin 5-HT2 Receptor Agonists);刺激, 化学性(Stimulation, Chemical);治疗结果(Treatment Outcome);血管收缩药(Vasoconstrictor Agents)

DOI 10.1016/j.pbb.2019.02.010

PMID 30811963

发布时间 2020-05-01

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Pharmacology, biochemistry, and behavior

2019年180卷

52-59页

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The serotonin-2C agonist Lorcaserin delays intravenous choice and modifies the subjective and cardiovascular effects of cocaine: A randomized, controlled human laboratory study.

Pharmacology, biochemistry, and behavior

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Pharmacology, biochemistry, and behavior

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The serotonin-2C agonist Lorcaserin delays intravenous choice and modifies the subjective and cardiovascular effects of cocaine: A randomized, controlled human laboratory study.

Pharmacology, biochemistry, and behavior

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Pharmacology, biochemistry, and behavior

相关期刊

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