Cancer associated fibroblasts sculpt tumour microenvironment by recruiting monocytes and inducing immunosuppressive PD-1<sup>+</sup> TAMs.
作者:
主题词
乳腺肿瘤(Breast Neoplasms);细胞分化(Cell Differentiation);细胞运动(Cell Movement);细胞增殖(Cell Proliferation);趋化因子CCL2(Chemokine CCL2);趋化因子CXCL12(Chemokine CXCL12);上皮-间质转化(Epithelial-Mesenchymal Transition);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);白细胞介素10(Interleukin-10);白细胞介素12(Interleukin-12);Ki-67抗原(Ki-67 Antigen);巨噬细胞活化(Macrophage Activation);巨噬细胞(Macrophages);单核细胞(Monocytes);肿瘤微环境(Tumor Microenvironment)
DOI
10.1038/s41598-019-39553-z
PMID
30816272
发布时间
2020-09-16
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Scientific reports
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