A signalling cascade involving receptor-activated phospholipase A<sub>2</sub>, glycerophosphoinositol 4-phosphate, Shp1 and Src in the activation of cell motility.

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第一作者： Alessia,Varone

第一单位： Institute of Protein Biochemistry, National Research Council, Via Pietro Castellino 111, 80131, Naples, Italy. a.varone@ibp.cnr.it.

作者： Alessia,Varone ^[1] ; Stefania,Mariggiò ^[2] ; Manpreet,Patheja ^[2] ; Vincenzo,Maione ^[3] ; Antonio,Varriale ^[2] ; Mariangela,Vessichelli ^[4] ; Daniela,Spano ^[2] ; Fabio,Formiggini ^[2] ; Matteo,Lo Monte ^[5] ; Nadia,Brancati ^[2] ; Maria,Frucci ^[6] ; Pompea,Del Vecchio ^[6] ; Sabato,D'Auria ^[7] ; Angela,Flagiello ^[2] ; Clara,Iannuzzi ^[4] ; Alberto,Luini ^[8] ; Piero,Pucci ^[2] ; Lucia,Banci ^[9] ; Carmen,Valente ^[2] ; Daniela,Corda ^[7]

作者单位： Institute of Protein Biochemistry, National Research Council, Via Pietro Castellino 111, 80131, Naples, Italy. a.varone@ibp.cnr.it. ^[1] Institute of Protein Biochemistry, National Research Council, Via Pietro Castellino 111, 80131, Naples, Italy. ^[2] Magnetic Resonance Centre (CERM), University of Florence, 50019, Sesto Fiorentino, Italy. ^[3] Institute of Food Science, National Research Council, Via Roma 64, 83100, Avellino, Italy. ^[4] Italian Institute of Technology, Centre for Advanced Biomaterials for Health Care at CRIB, Largo Barsanti e Matteucci 53, 80125, Naples, Italy. ^[5] Institute of High Performance Computing and Networking, National Research Council, Via P. Castellino 111, 80131, Naples, Italy. ^[6] Department of Chemical Sciences, University of Naples Federico II, Via Cintia, 80126, Naples, Italy. ^[7] CEINGE Advanced Biotechnology, Via G. Salvatore 486, 80145, Naples, Italy. ^[8] Department of Biochemistry, Biophysics and General Pathology, Second University of Naples, Via L. de Crecchio 7, 80138, Naples, Italy. ^[9] Institute of Protein Biochemistry, National Research Council, Via Pietro Castellino 111, 80131, Naples, Italy. d.corda@ibp.cnr.it. ^[10]

关键词 Actin polymerisation Cell motility EGF Glycerophosphoinositols Membrane ruffles Phosphoinositides SH2 domain Shp1