Molecular Design of HER3-Targeting Affibody Molecules: Influence of Chelator and Presence of HEHEHE-Tag on Biodistribution of <sup>68</sup>Ga-Labeled Tracers.
第一作者:
Charles,Dahlsson Leitao
第一单位:
Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, 106 91 Stockholm, Sweden. chdl@kth.se.
作者:
医学主题词
乙酸盐类(Acetates);动物(Animals);细胞系, 肿瘤(Cell Line, Tumor);螯合剂(Chelating Agents);镓放射性同位素(Gallium Radioisotopes);杂环化合物, 1环(Heterocyclic Compounds, 1-Ring);人类(Humans);肝(Liver);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 裸(Mice, Nude);正电子发射断层显像术(Positron-Emission Tomography);蛋白质结合(Protein Binding);放射性药物(Radiopharmaceuticals);重组融合蛋白质类(Recombinant Fusion Proteins);组织分布(Tissue Distribution)
DOI
10.3390/ijms20051080
PMID
30832342
发布时间
2020-02-25
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