Modeling to capture bystander-killing effect by released payload in target positive tumor cells.

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作者： Jong Hyuk,Byun ^[1] ; Il Hyo,Jung ^[2]

作者单位： Department of Mathematics, Pusan National University, Busan, 46241, South Korea. ^[1] Department of Mathematics, Pusan National University, Busan, 46241, South Korea. ilhjung@pusan.ac.kr. ^[2]

关键词 Age-structure model Antibody-drug conjugates (ADCs)Bystander-killing effect in ADCs Dose-response curve Tumor growth inhibition (TGI) model

主题词抗肿瘤药(Antineoplastic Agents);剂量效应关系, 药物(Dose-Response Relationship, Drug);人类(Humans);免疫轭合物(Immunoconjugates);免疫因子类(Immunologic Factors);模型, 生物学(Models, Biological);肿瘤(Neoplasms)

DOI 10.1186/s12885-019-5336-7

PMID 30832603

发布时间 2020-02-25

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BMC cancer

2019年19卷1期

194页

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Modeling to capture bystander-killing effect by released payload in target positive tumor cells.

BMC cancer

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BMC cancer

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Modeling to capture bystander-killing effect by released payload in target positive tumor cells.

BMC cancer

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BMC cancer

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