Metabolites Involved in Immune Evasion by <i>Batrachochytrium dendrobatidis</i> Include the Polyamine Spermidine.

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作者： Louise A,Rollins-Smith ^[1] ; Antonio C,Ruzzini ^[2] ; J Scott,Fites ^[3] ; Laura K,Reinert ^[4] ; Emily M,Hall ^[2] ; Bryan A,Joosse ^[5] ; Vishvaas I,Ravikumar ^[5] ; Megan I,Huebner ^[2] ; Audrey,Aka ^[5] ; Miles H,Kehs ^[5] ; Bria M,Gillard ^[5] ; Emily,Doe ^[6] ; Julia A,Tasca ^[6] ; Thomas P,Umile ^[7] ; Jon,Clardy ^[7] ; Kevin P C,Minbiole ^[6]

作者单位： Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA louise.rollins-smith@vanderbilt.edu. ^[1] Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee, USA. ^[2] Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA. ^[3] Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, USA. ^[4] Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA. ^[5] Division of Natural and Computational Sciences, Gwynedd Mercy University, Gwynedd Valley, Pennsylvania, USA. ^[6] Department of Chemistry, Villanova University, Villanova, Pennsylvania, USA. ^[7]

关键词 Batrachochytrium dendrobatidis amphibian declines difluoromethylarginine (DFMA)difluoromethylornithine (DFMO)immunomodulation methylthioadenosine polyamine putrescine spermidine splenocytes