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Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer.

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第一作者: Kirsten L,Bryant
第一单位: Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
作者单位: Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. [1] Cancer and Cell Biology Division, Translational Genomics Research Institute, Phoenix, AZ, USA. [2] Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. [3] Eppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE, USA. [4] Center for Applied Proteomics and Molecular Medicine, George Mason University, Fairfax, VA, USA. [5] Department of Molecular and Cellular Oncology, Division of Basic Science Research, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. [6] Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. [7] Sarah W. Stedman Nutrition and Metabolism Center & Duke Molecular Physiology Institute, Department of Medicine, Duke University, Durham, NC, USA. [8] Center for Personalized Medicine, Roswell Park Cancer Center, Buffalo, NY, USA. [9] Department of Molecular and Cell Biology, Roswell Park Cancer Center, Buffalo, NY, USA. [10] Department of Cancer Biology, Mayo Clinic, Phoenix, AZ, USA. [11] Department of Molecular and Integrative Physiology; Department of Internal Medicine, Division of Gastroenterology and University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, USA. [12] Perlmutter Cancer Center, NYU Langone Medical Center, New York City, NY, USA. [13] Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.;Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.;Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. [14] Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. cjder@med.unc.edu.;Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. cjder@med.unc.edu.;Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. cjder@med.unc.edu. [15]
DOI 10.1038/s41591-019-0368-8
PMID 30833752
发布时间 2024-07-16
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