A lower impact of an acute exposure to electronic cigarette aerosols than to cigarette smoke in human organotypic buccal and small airway cultures was demonstrated using systems toxicology assessment.

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作者： Anita R,Iskandar ^[1] ; Filippo,Zanetti ^[2] ; Athanasios,Kondylis ^[2] ; Florian,Martin ^[2] ; Patrice,Leroy ^[2] ; Shoaib,Majeed ^[2] ; Sandro,Steiner ^[2] ; Yang,Xiang ^[2] ; Laura,Ortega Torres ^[2] ; Keyur,Trivedi ^[2] ; Emmanuel,Guedj ^[2] ; Celine,Merg ^[2] ; Stefan,Frentzel ^[2] ; Nikolai V,Ivanov ^[2] ; Utkarsh,Doshi ^[3] ; Kyeonghee Monica,Lee ^[3] ; Willie J,McKinney ^[3] ; Manuel C,Peitsch ^[2] ; Julia,Hoeng ^[2]

作者单位： Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland. Anita.Iskandar@pmi.com. ^[1] Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland. ^[2] Altria Client Services LLC, Richmond, VA, 23219, USA. ^[3]

关键词 E-cigarettes Oral Organotypic cultures Small airway Systems toxicology Transcriptomics

主题词环境暴露(Environmental Exposure);人类(Humans);口腔黏膜(Mouth Mucosa)

DOI 10.1007/s11739-019-02055-x

PMID 30835057

发布时间 2023-10-13

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准确一般字义偏差语意偏离译文作用小提交