A small-molecule fusion inhibitor of influenza virus is orally active in mice.

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第一作者： Maria J P,van Dongen

第一单位： Janssen Prevention Center, Janssen Pharmaceutical Companies of Johnson & Johnson, Archimedesweg 6, Leiden, Netherlands. mvandon@its.jnj.com wilson@scripps.edu.

作者： Maria J P,van Dongen ^[1] ; Rameshwar U,Kadam ^[2] ; Jarek,Juraszek ^[3] ; Edward,Lawson ^[4] ; Boerries,Brandenburg ^[5] ; Frederike,Schmitz ^[4] ; Wim B G,Schepens ^[6] ; Bart,Stoops ^[4] ; Harry A,van Diepen ^[2] ; Mandy,Jongeneelen ^[2] ; Chan,Tang ^[4] ; Jan,Vermond ^[4] ; Alida,van Eijgen-Obregoso Real ^[6] ; Sven,Blokland ^[4] ; Divita,Garg ^[6] ; Wenli,Yu ^[4] ; Wouter,Goutier ^[4] ; Ellen,Lanckacker ^[4] ; Jaco M,Klap ^[6] ; Daniëlle C G,Peeters ^[7] ; Jin,Wu ^[3] ; Christophe,Buyck ^[4] ; Tim H M,Jonckers ^[8] ; Dirk,Roymans ^[4] ; Peter,Roevens ^[2] ; Ronald,Vogels ^[8] ; Wouter,Koudstaal ^[2] ; Robert H E,Friesen ^[8] ; Pierre,Raboisson ^[8] ; Dashyant,Dhanak ^[2] ; Jaap,Goudsmit ^[4] ; Ian A,Wilson ^[6]

作者单位： Janssen Prevention Center, Janssen Pharmaceutical Companies of Johnson & Johnson, Archimedesweg 6, Leiden, Netherlands. mvandon@its.jnj.com wilson@scripps.edu. ^[1] Discovery Sciences, Janssen Research & Development, Turnhoutseweg 30, Beerse, Belgium. ^[2] Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA. ^[3] Janssen Prevention Center, Janssen Pharmaceutical Companies of Johnson & Johnson, Archimedesweg 6, Leiden, Netherlands. ^[4] Discovery Sciences, Janssen Research & Development, 1400 McKean Rd., Spring House, PA, USA. ^[5] Janssen Infectious Diseases and Vaccines, Janssen Research & Development, Archimedesweg 4-6, Leiden, Netherlands. ^[6] Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA. ^[7] Janssen Infectious Diseases and Vaccines, Janssen Research & Discovery, Turnhoutseweg 30, Beerse, Belgium. ^[8] Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA. ^[9] Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA. mvandon@its.jnj.com wilson@scripps.edu. ^[10] The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA, USA. ^[11]