换一批Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02.
第一作者：
Christos,Tziotzios
第一单位：
St. John's Institute of Dermatology, King's College London, London, Guy's Hospital, London, SE1 9RT, UK. christos.tziotzios@kcl.ac.uk.
作者：
Christos,Tziotzios [1]
;
Christos,Petridis [2]
;
Nick,Dand [2]
;
Chrysanthi,Ainali [3]
;
Jake R,Saklatvala [2]
;
Venu,Pullabhatla [4]
;
Alexandros,Onoufriadis [3]
;
Rashida,Pramanik [4]
;
David,Baudry [3]
;
Sang Hyuck,Lee [5]
;
Kristie,Wood [4]
;
Lu,Liu [6]
;
Seth,Seegobin [3]
;
Gregory A,Michelotti [7]
;
Su M,Lwin [3]
;
Evangelos A A,Christou [3]
;
Charles J,Curtis [4]
;
Emanuele,de Rinaldis [4]
;
Alka,Saxena [4]
;
Susan,Holmes [8]
;
Matthew,Harries [9]
;
Ioulios,Palamaras [10]
;
Fiona,Cunningham [8]
;
Gregory,Parkins [8]
;
Manjit,Kaur [11]
;
Paul,Farrant [12]
;
Andrew,McDonagh [13]
;
Andrew,Messenger [13]
;
Jennifer,Jones [14]
;
Victoria,Jolliffe [15]
;
Iaisha,Ali [16]
;
Michael,Ardern-Jones [17]
;
Charles,Mitchell [18]
;
Nigel,Burrows [19]
;
Ravinder,Atkar [19]
;
Cedric,Banfield [20]
;
Anton,Alexandroff [21]
;
Caroline,Champagne [22]
;
Hywel L,Cooper [18]
;
Sergio,Vañó-Galván [23]
;
Ana Maria,Molina-Ruiz [24]
;
Nerea Ormaechea,Perez [25]
;
Girish K,Patel [26]
;
Abby,Macbeth [27]
;
Melanie,Page [27]
;
Alyson,Bryden [28]
;
Megan,Mowbray [29]
;
Shyamal,Wahie [30]
;
Keith,Armstrong [31]
;
Nicola,Cooke [32]
;
Mark,Goodfield [33]
;
Irene,Man [34]
;
David,de Berker [35]
;
Giles,Dunnill [35]
;
Anita,Takwale [36]
;
Archana,Rao [37]
;
Tee-Wei,Siah [38]
;
Rodney,Sinclair [39]
;
Martin S,Wade [40]
;
Ncoza C,Dlova [41]
;
Jane,Setterfield [3]
;
Fiona,Lewis [3]
;
Kapil,Bhargava [3]
;
Niall,Kirkpatrick [42]
;
Xavier,Estivill [43]
;
Catherine M,Stefanato [44]
;
Carsten,Flohr [3]
;
Timothy,Spector [45]
;
Fiona M,Watt [46]
;
Catherine H,Smith [3]
;
Jonathan N,Barker [3]
;
David A,Fenton [3]
;
Michael A,Simpson [2]
;
John A,McGrath [47]
作者单位：
St. John's Institute of Dermatology, King's College London, London, Guy's Hospital, London, SE1 9RT, UK. christos.tziotzios@kcl.ac.uk.
[1]
Department of Medical and Molecular Genetics, King's College London, Guy's Hospital, London, SE1 9RT, UK.
[2]
St. John's Institute of Dermatology, King's College London, London, Guy's Hospital, London, SE1 9RT, UK.
[3]
UK NIHR GSTFT/KCL Comprehensive Biomedical Research Centre, Guy's & St. Thomas' NHS Foundation Trust, London, SE1 9RT, UK.
[4]
NIHR Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust (SLaM) & Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, Denmark Hill Campus, London, SE5 8EF, UK.
[5]
National Diagnostic EB Laboratory, St. Thomas Hospital, London, SE1 7EH, UK.
[6]
Metabolon, Inc., Morrisville, NC, 27560, USA.
[7]
Alan Lyell Centre for Dermatology, Queen Elizabeth University Hospital, Glasgow, G51 4TF, UK.
[8]
The Dermatology Centre, The University of Manchester, Salford Royal NHS Foundation Trust, Salford, M6 8HD, UK.
[9]
Department of Dermatology, Barnet General Hospital, Royal Free Foundation Trust, London, EN5 3DJ, UK.
[10]
Department of Dermatology, Solihull Hospital, Solihull, B91 2JL, UK.
[11]
Department of Dermatology, Brighton and Sussex University Hospitals NHS Trust, Brighton, BN2 3EW, UK.
[12]
Department of Dermatology, Royal Hallamshire Hospital, Sheffield, S10 2JF, UK.
[13]
Department of Dermatology, Royal Free Hospital, London, NW3 2QG, UK.
[14]
Department of Dermatology, Royal London Hospital, Barts Health NHS Trust, London, E1 1BB, UK.
[15]
Department of Dermatology, Imperial College Healthcare NHS Trust, London, W12 0HS, UK.
[16]
Department of Dermatology, University Hospitals Southampton NHS Foundation Trust, Southampton, SO16 6YD, UK.
[17]
Department of Dermatology, Portsmouth Hospitals NHS Trust, Portsmouth, PO6 3LY, UK.
[18]
Department of Dermatology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK.
[19]
Department of Dermatology, Peterborough City Hospital, Peterborough, PE3 9GZ, UK.
[20]
Department of Dermatology, University Hospitals of Leicester, Leicester Royal Infirmary, Leicester, LE3 9QP, UK.
[21]
Department of Dermatology, The Churchill Hospital, Oxford, OX3 7LE, UK.
[22]
Trichology Unit, Dermatology Department, Ramon Y Cajal Hospital, University of Alcala, IRYCIS, Madrid, 28034, Spain.
[23]
Hospital Universitario Fundación Jiménez Díaz, Madrid, 28040, Spain.
[24]
Department of Dermatology, Hospital Donostia, San Sebastian, 20014, Spain.
[25]
Hywel Dda University Health Board, Cardiff, SA31 3BB, UK.
[26]
Department of Dermatology, Norfolk & Norwich University Hospitals NHS Foundation Trust, Norwich, NR4 7UY, UK.
[27]
Department of Dermatology, Ninewells Hospital, Dundee, DD1 9SY, UK.
[28]
Department of Dermatology, Queen Margaret Hospital, Dunfermline, KY12 0SU, UK.
[29]
Department of Dermatology, County Durham and Darlington NHS Foundation Trust, Darlington, DL3 6HX, UK.
[30]
Department of Dermatology, Royal Victoria Hospital, Belfast, BT12 6BA, UK.
[31]
Department of Dermatology, Whiteabbey Hospital, Northern Health & Social Care Trust, Co Antrim, BT37 9RH, UK.
[32]
Department of Dermatology, Chapel Allerton Hospital, Leeds teaching Hospitals NHS Trust, Leeds, LS7 4SA, UK.
[33]
Department of Dermatology, Surrey and Sussex Healthcare NHS Trust, Surrey, RH1 5RH, UK.
[34]
Department of Dermatology, University Hospitals Bristol NHS Foundation Trust, Bristol, BS2 8HW, UK.
[35]
Department of Dermatology, Gloucestershire Hospitals NHS Foundation Trust, Gloucester, GL1 3NN, UK.
[36]
Department of Dermatology, Kingston Hospital NHS Foundation Trust, Kingston-upon-Thames, KT2 7QB, UK.
[37]
Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, NE1 4LP, UK.
[38]
Department of Dermatology, University of Melbourne, Melbourne, VIC 3010, Australia.
[39]
The London Skin and Hair Clinic, London, WC1V 7DN, UK.
[40]
Department of Dermatology, School of Clinical Medicine, Nelson R Mandela School of Medicine, Durban, 4001, South Africa.
[41]
Craniofacial Surgery Unit, Chelsea & Westminster Hospital, London, SW10 9NH, UK.
[42]
Genetics Unit, Dexeus Women's Health, Barcelona, 08028, Spain.
[43]
Department of Dermatopathology, St. John's Institute of Dermatology, St. Thomas' Hospital, London, SE1 7EH, UK.
[44]
The Department of Twin Research & Genetic Epidemiology, King's College London, London, SE1 7EH, UK.
[45]
Centre for Stem Cells and Regenerative Medicine, King's College London, Guy's Hospital, London, SE1 9RT, UK.
[46]
St. John's Institute of Dermatology, King's College London, London, Guy's Hospital, London, SE1 9RT, UK. john.mcgrath@kcl.ac.uk.
[47]
医学主题词
适应性免疫(Adaptive Immunity);秃发(Alopecia);病例对照研究(Case-Control Studies);队列研究(Cohort Studies);女(雌)性(Female);基因表达(Gene Expression);基因座(Genetic Loci);疾病遗传易感性(Genetic Predisposition to Disease);基因组, 人(Genome, Human);全基因组关联研究(Genome-Wide Association Study);HLA-B7抗原(HLA-B7 Antigen);人类(Humans);免疫, 先天(Immunity, Innate);多态性, 单核苷酸(Polymorphism, Single Nucleotide)
DOI
10.1038/s41467-019-09117-w
PMID
30850646
发布时间
2025-05-30
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Nature communications
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