Investigation into the use of histone deacetylase inhibitor MS-275 as a topical agent for the prevention and treatment of cutaneous squamous cell carcinoma in an SKH-1 hairless mouse model.
作者:
主题词
投药, 局部(Administration, Topical);动物(Animals);苯甲酰胺类(Benzamides);癌, 鳞状细胞(Carcinoma, Squamous Cell);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);细胞存活(Cell Survival);周期素依赖激酶抑制剂p21(Cyclin-Dependent Kinase Inhibitor p21);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);组蛋白脱乙酰基酶抑制剂(Histone Deacetylase Inhibitors);人类(Humans);小鼠(Mice);小鼠, 无毛(Mice, Hairless);肿瘤, 辐射性(Neoplasms, Radiation-Induced);吡啶类(Pyridines);皮肤肿瘤(Skin Neoplasms);肿瘤负荷(Tumor Burden);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1371/journal.pone.0213095
PMID
30865688
发布时间
2024-04-11
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PloS one
e0213095页
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