Synthesis and Antitumor Activity of a Series of Novel 1-Oxa-4-azaspiro[4,5]deca-6,9-diene-3,8-dione Derivatives.

导出 OA

翻译打印收藏纠错

作者： Ze,Yang ^[1] ; Qiu,Zhong ^[2] ; Shilong,Zheng ^[3] ; Guangdi,Wang ^[4] ; Ling,He ^[5]

作者单位： Key Laboratory of Drug⁻Targeting and Drug Delivery System of the Education Ministry, Department of Medicinal Chemistry, West China School of Pharmacy, Sichuan University, Chengdu 610041, Sichuan, China. 2016224055105@stu.scu.edu.cn. ^[1] Sichuan Engineering Laboratory for Plant⁻Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, Department of Medicinal Chemistry, West China School of Pharmacy, Sichuan University, Chengdu 610041, Sichuan, China. 2016224055105@stu.scu.edu.cn. ^[2] Department of Chemistry, RCMI Cancer Research Center, Xavier University of Louisiana, New Orleans, LA 70125, USA. qzhong@xula.edu. ^[3] Department of Chemistry, RCMI Cancer Research Center, Xavier University of Louisiana, New Orleans, LA 70125, USA. szheng@xula.edu. ^[4] Department of Chemistry, RCMI Cancer Research Center, Xavier University of Louisiana, New Orleans, LA 70125, USA. gwang@xula.edu. ^[5] Key Laboratory of Drug⁻Targeting and Drug Delivery System of the Education Ministry, Department of Medicinal Chemistry, West China School of Pharmacy, Sichuan University, Chengdu 610041, Sichuan, China. heling2012@scu.edu.cn. ^[6]

关键词 1-oxa-4-azaspiro[4.5]deca-6,9-diene-3,8-dione antitumor activity intramolecular oxidation