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Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition.

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第一作者： Anna,Cuppari

第一单位： Proteolysis Laboratory, Department of Structural Biology, Molecular Biology Institute of Barcelona, CSIC, Barcelona Science Park, Helix Building, c/o Baldiri Reixac 15-21, E-08028 Barcelona, Catalonia, Spain.

作者： Anna,Cuppari ^[1] ; Hagen,Körschgen ^[2] ; Dirk,Fahrenkamp ^[3] ; Carlo,Schmitz ^[4] ; Tibisay,Guevara ^[1] ; Konstantin,Karmilin ^[2] ; Michael,Kuske ^[2] ; Mario,Olf ^[2] ; Eileen,Dietzel ^[3] ; Irene,Yiallouros ^[2] ; Daniele,de Sanctis ^[5] ; Theodoros,Goulas ^[1] ; Ralf,Weiskirchen ^[6] ; Willi,Jahnen-Dechent ^[4] ; Julia,Floehr ^[4] ; Walter,Stoecker ^[2] ; Luca,Jovine ^[3] ; F Xavier,Gomis-Rüth ^[1]

作者单位： Proteolysis Laboratory, Department of Structural Biology, Molecular Biology Institute of Barcelona, CSIC, Barcelona Science Park, Helix Building, c/o Baldiri Reixac 15-21, E-08028 Barcelona, Catalonia, Spain. ^[1] Institute of Molecular Physiology, Cell and Matrix Biology, Johannes Gutenberg-University Mainz, Johann-Joachim-Becher-Weg 7, D-55128 Mainz, Germany. ^[2] Department of Biosciences and Nutrition and Center for Innovative Medicine, Karolinska Institutet, Blickagången 16, SE-141 83 Huddinge, Sweden. ^[3] Biointerface Laboratory, Helmholtz Institute for Biomedical Engineering, RWTH Aachen University Medical Faculty, Pauwelsstrasse 30, D-52074 Aachen, Germany. ^[4] ESRF - The European Synchrotron, 71 Rue Jules Horowitz, F-38000 Grenoble, France. ^[5] Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry, RWTH Aachen University Hospital, Pauwelsstrasse 30, D-52074 Aachen, Germany. ^[6]

关键词 X-ray crystallography enzyme mechanisms mammalian fertilization metallopeptidase multi-protein complexes polyspermy protein inhibitor protein structure sperm–egg fusion structure determination

DOI 10.1107/S2052252519001568

PMID 30867929

发布时间 2024-07-14

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IUCrJ

2019年6卷Pt 2期

317-330页

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2019年6卷Pt 2期

317-330页

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Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition.

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Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition.

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