KRAS, NRAS, and BRAF mutations are highly enriched in trisomy 12 chronic lymphocytic leukemia and are associated with shorter treatment-free survival.

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第一作者： Elena,Vendramini

第一单位： Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano (PN), Italy.

作者： Elena,Vendramini ^[1] ; Riccardo,Bomben ^[1] ; Federico,Pozzo ^[1] ; Dania,Benedetti ^[1] ; Tamara,Bittolo ^[1] ; Francesca Maria,Rossi ^[1] ; Michele,Dal Bo ^[1] ; Kari G,Rabe ^[2] ; Gabriele,Pozzato ^[3] ; Francesco,Zaja ^[3] ; Annalisa,Chiarenza ^[4] ; Francesco,Di Raimondo ^[4] ; Esteban,Braggio ^[5] ; Sameer A,Parikh ^[5] ; Neil E,Kay ^[5] ; Tait D,Shanafelt ^[6] ; Giovanni,Del Poeta ^[7] ; Valter,Gattei ^[8] ; Antonella,Zucchetto ^[9]

作者单位： Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano (PN), Italy. ^[1] Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA. ^[2] Department of Internal Medicine and Haematology, Maggiore General Hospital, University of Trieste, Trieste, Italy. ^[3] Division of Hematology, Ferrarotto Hospital, Catania, Italy. ^[4] Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, USA. ^[5] Department of Hematology/Oncology, Stanford University, Stanford, CA, USA. ^[6] Division of Hematology, S. Eugenio Hospital and University of Tor Vergata, Rome, Italy. ^[7] Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano (PN), Italy. vgattei@cro.it. ^[8] Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano (PN), Italy. zucchetto.soecs@cro.it. ^[9]