Integrin alpha x stimulates cancer angiogenesis through PI3K/Akt signaling-mediated VEGFR2/VEGF-A overexpression in blood vessel endothelial cells.
第一作者:
Jingshu,Wang
第一单位:
Central Laboratory, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
作者:
主题词
动物(Animals);细胞运动(Cell Movement);细胞增殖(Cell Proliferation);鸡胚(Chick Embryo);基因敲低技术(Gene Knockdown Techniques);HEK293细胞(HEK293 Cells);人类(Humans);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 裸(Mice, Nude);新生血管化, 病理性(Neovascularization, Pathologic);新生血管化, 生理性(Neovascularization, Physiologic);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);原癌基因蛋白质c-myc(Proto-Oncogene Proteins c-myc);信号传导(Signal Transduction);转染(Transfection);肿瘤负荷(Tumor Burden);血管内皮生长因子A(Vascular Endothelial Growth Factor A);血管内皮生长因子受体2(Vascular Endothelial Growth Factor Receptor-2)
DOI
10.1002/jcb.27480
PMID
30873824
发布时间
2020-02-26
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Journal of cellular biochemistry
1807-1818页
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