换一批
换一批Supercoil Levels in <i>E. coli</i> and <i>Salmonella</i> Chromosomes Are Regulated by the C-Terminal 35⁻38 Amino Acids of GyrA.
第一作者：
Nikolay S,Rovinskiy
第一单位：
Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294-0024, USA. nikolay.rovinskiy@aol.com.
作者：
关键词
DNA gyrase is an enzyme with two protein subunitsDNA topology is investigated that involves two types of DNA coilingGyrA and GyrB that catalyzes (?) supercoiling at the expense of ATP hydrolysisRNA polymerase (RNAP)gamma delta (γδ) resolvase is a site-specific recombinase from the γδ transposon the that utilizes (?) supercoils to delete a DNA sequence that is flanked by 100 bp Res sitesgyrase processivity refers to the number of reaction cycles one enzyme carries out in a single DNA binding eventthe E. coli and Salmonella condensin is a multi-protein complex composed of three proteins, MukB, MukE, and MukF that compacts chromosomal DNAthe GyrA C-terminal domain (CTD) includes a long DNA binding section that has 6 pinwheel elements plus a short 35–38 amino acid terminus called the tailthe Q10 rule states that reaction rates double for every 10° C increase in temperaturethe first type is right-handed coils that Watson/Crick DNA strands adopt by winding around each other every 10.6 base pairs, the second type involves coiling of the double strands around each other in either a left handed (?) or right handed (+) direction
DOI
10.3390/microorganisms7030081
PMID
30875939
发布时间
2024-07-15
- 浏览17
Microorganisms
2019年7卷3期
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