Antimicrobial activity of Phyllanthus amarus Schumach. & Thonn and inhibition of the NorA efflux pump of Staphylococcus aureus by Phyllanthin.

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第一作者： Alessandra Maria,Braga Ribeiro

第一单位： Medicinal Plants Research Center, Federal University of Piaui, Teresina, Piaui, Brazil.

作者： Alessandra Maria,Braga Ribeiro ^[1] ; Jonas Nascimento de,Sousa ^[2] ; Luciana Muratori,Costa ^[2] ; Felipe Araújo de Alcântara,Oliveira ^[2] ; Raimunda Cardoso,Dos Santos ^[3] ; Aline Suelen,Silva Nunes ^[1] ; Wanderson Oliveira,da Silva ^[4] ; Paulo Jorge,Marques Cordeiro ^[4] ; José,de Sousa Lima Neto ^[5] ; José Pinto,de Siqueira-Júnior ^[6] ; Glenn William,Kaatz ^[7] ; Humberto Medeiros,Barreto ^[8] ; Aldeídia Pereira,de Oliveira ^[1]

作者单位： Medicinal Plants Research Center, Federal University of Piaui, Teresina, Piaui, Brazil. ^[1] Laboratory of Research in Microbiology, Federal University of Piaui, Teresina, Piaui, Brazil. ^[2] Nucleus of Research in Biodiversity and Biotechnology, Biotec, Federal University of Piaui, Parnaiba, Piaui, Brazil. ^[3] Institute of Chemistry of São Carlos, University of São Paulo, São Paulo, Brazil. ^[4] Laboratory of Organic Geochemistry, Federal University of Piaui, Teresina, Piauí, Brazil. ^[5] Laboratory of Genetics of Microorganisms, Federal University of Paraiba, Joao Pessoa, Paraiba, Brazil. ^[6] Department of Medicine, Division of Infectious Diseases, Wayne State University School of Medicine, Detroit, MI, USA. ^[7] Laboratory of Research in Microbiology, Federal University of Piaui, Teresina, Piaui, Brazil. Electronic address: hmbarreto@ufpi.edu.br. ^[8]

关键词 Bacterial resistance Efflux pumps Fluoroquinolones Phyllanthin Phyllanthus amarus Staphylococcus aureus