miR-577 Regulates TGF-β Induced Cancer Progression through a SDPR-Modulated Positive-Feedback Loop with ERK-NF-κB in Gastric Cancer.
作者:
主题词
动物(Animals);细胞系, 肿瘤(Cell Line, Tumor);疾病恶化(Disease Progression);上皮-间质转化(Epithelial-Mesenchymal Transition);反馈, 生理(Feedback, Physiological);HEK293细胞(HEK293 Cells);人类(Humans);MAP激酶信号系统(MAP Kinase Signaling System);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 裸(Mice, Nude);微RNAs(MicroRNAs);NF-κB(NF-kappa B);磷酸结合蛋白质类(Phosphate-Binding Proteins);质粒(Plasmids);预后(Prognosis);RNA, 小分子干扰(RNA, Small Interfering);胃肿瘤(Stomach Neoplasms);存活率(Survival Rate);转录激活(Transcriptional Activation);转染(Transfection);转化生长因子β(Transforming Growth Factor beta);肿瘤负荷(Tumor Burden);增量调节(Up-Regulation)
DOI
10.1016/j.ymthe.2019.02.002
PMID
30879950
发布时间
2020-06-05
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Molecular therapy
1166-1182页
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