第一单位:
David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; MIT Center for Precision Cancer Medicine, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
作者:
Nicholas B,Struntz [1]
;
Andrew,Chen [1]
;
Anja,Deutzmann [2]
;
Robert M,Wilson [1]
;
Eric,Stefan [3]
;
Helen L,Evans [1]
;
Maricela A,Ramirez [4]
;
Tong,Liang [4]
;
Francisco,Caballero [3]
;
Mattheus H E,Wildschut [3]
;
Dylan V,Neel [3]
;
David B,Freeman [5]
;
Marius S,Pop [5]
;
Marie,McConkey [6]
;
Sandrine,Muller [7]
;
Brice H,Curtin [1]
;
Hanna,Tseng [3]
;
Kristen R,Frombach [3]
;
Vincent L,Butty [8]
;
Stuart S,Levine [8]
;
Clementine,Feau [7]
;
Sarah,Elmiligy [9]
;
Jiyoung A,Hong [10]
;
Timothy A,Lewis [7]
;
Amedeo,Vetere [7]
;
Paul A,Clemons [7]
;
Scott E,Malstrom [9]
;
Benjamin L,Ebert [6]
;
Charles Y,Lin [11]
;
Dean W,Felsher [2]
;
Angela N,Koehler [12]
作者单位:
David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; MIT Center for Precision Cancer Medicine, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
[1]
Division of Oncology, Departments of Medicine and Pathology Stanford School of Medicine, Stanford, CA 94305, USA.
[2]
David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
[3]
Department of Molecular and Human Genetics and Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
[4]
David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Kronos Bio, Inc., Cambridge, MA 02139, USA.
[5]
Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
[6]
Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
[7]
David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; BioMicro Center, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
[8]
David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
[9]
David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, MA 02115, USA.
[10]
Department of Molecular and Human Genetics and Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Therapeutic Innovation Center, Baylor College of Medicine, Houston, TX 77030, USA.
[11]
David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; MIT Center for Precision Cancer Medicine, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address: koehler@mit.edu.
[12]
主题词
动物(Animals);碱性螺旋-环-螺旋亮氨酸拉链转录因子类(Basic Helix-Loop-Helix Leucine Zipper Transcription Factors);细胞系(Cell Line);二聚作用(Dimerization);疾病模型, 动物(Disease Models, Animal);人类(Humans);内酰胺类(Lactams);男(雄)性(Male);小鼠(Mice);小鼠, 近交NOD(Mice, Inbred NOD);小鼠, SCID(Mice, SCID);肿瘤(Neoplasms);多环化合物(Polycyclic Compounds);启动区, 遗传(Promoter Regions, Genetic);蛋白质结合(Protein Binding);原癌基因蛋白质c-myc(Proto-Oncogene Proteins c-myc);大鼠(Rats);阻遏蛋白质类(Repressor Proteins);小分子化合物库(Small Molecule Libraries);转录, 遗传(Transcription, Genetic);紫外线(Ultraviolet Rays)
DOI
10.1016/j.chembiol.2019.02.009
PMID
30880155
发布时间
2020-05-11