Targeting the tumor microenvironment to overcome immune checkpoint blockade therapy resistance.

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第一作者： Yaqi,Li

第一单位： Center of Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, Suzhou Institute of Systems Medicine, Suzhou, Jiangsu, China.

作者： Yaqi,Li ^[1] ; Jing,Liu ^[1] ; Long,Gao ^[1] ; Yuan,Liu ^[1] ; Fang,Meng ^[1] ; Xiaoan,Li ^[2] ; F Xiao-Feng,Qin ^[3]

作者单位： Center of Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, Suzhou Institute of Systems Medicine, Suzhou, Jiangsu, China. ^[1] The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, China. Electronic address: 435445611@qq.com. ^[2] Center of Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, Suzhou Institute of Systems Medicine, Suzhou, Jiangsu, China. Electronic address: fqin1@foxmail.com. ^[3]

关键词 CTLA-4 Cancer immunotherapy Immune checkpoint blockade resistance PD-1/PD-L1 Tumor microenvironment

主题词抗药性, 肿瘤(Drug Resistance, Neoplasm);人类(Humans);免疫疗法(Immunotherapy);肿瘤(Neoplasms);信号传导(Signal Transduction);肿瘤微环境(Tumor Microenvironment)

DOI 10.1016/j.imlet.2019.03.006

PMID 30885690

发布时间 2020-12-17

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