S100A4 alters metabolism and promotes invasion of lung cancer cells by up-regulating mitochondrial complex I protein NDUFS2.
作者:
关键词
NADH:ubiquinone oxidoreductase core subunit S2 (NDUFS2)S100 calcium-binding protein A4 (S100A4)S100 proteinscellular respirationenergy metabolismfibroblast-specific protein-1glycolysisinvasionlung cancermetastasin-1metastasismitochondriamitochondrial complex Imitochondrial respiratory chain complexnon-small cell lung cancer (NSCLC)
主题词
腺苷三磷酸(Adenosine Triphosphate);细胞系, 肿瘤(Cell Line, Tumor);基因沉默(Gene Silencing);糖酵解(Glycolysis);人类(Humans);肺肿瘤(Lung Neoplasms);NADH脱氢酶(NADH Dehydrogenase);肿瘤侵润(Neoplasm Invasiveness);肿瘤转移(Neoplasm Metastasis);信号传导(Signal Transduction);增量调节(Up-Regulation)
DOI
10.1074/jbc.RA118.004365
PMID
30885944
发布时间
2022-11-17
- 浏览14

The Journal of biological chemistry
7516-7527页
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