Constitutive STAT3 phosphorylation and IL-6/IL-10 co-expression are associated with impaired T-cell function in tuberculosis patients.

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作者： Kirstin,Harling ^[1] ; Ernest,Adankwah ^[1] ; Alptekin,Güler ^[1] ; Anthony,Afum-Adjei Awuah ^[2] ; Louis,Adu-Amoah ^[3] ; Ertan,Mayatepek ^[2] ; Ellis,Owusu-Dabo ^[1] ; Norman,Nausch ^[2] ; Marc,Jacobsen ^[3]

作者单位： Department of General Pediatrics, Neonatology, and Pediatric Cardiology, University Children's Hospital, 40225, Duesseldorf, Germany. ^[1] Kumasi Centre for collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana. ^[2] School of Public Health, College of Health Sciences, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana. ^[3] Department of General Pediatrics, Neonatology, and Pediatric Cardiology, University Children's Hospital, 40225, Duesseldorf, Germany. marc.jacobsen@med.uni-duesseldorf.de. ^[4]

关键词 Interleukin-10 Interleukin-6 SOCS3 STAT3 tuberculosis

主题词成年人(Adult);老年人(Aged);细胞, 培养的(Cells, Cultured);女(雌)性(Female);基因表达调控(Gene Expression Regulation);人类(Humans);白细胞介素10(Interleukin-10);白细胞介素6(Interleukin-6);男(雄)性(Male);中年人(Middle Aged);结核分枝杆菌(Mycobacterium tuberculosis);磷酰化(Phosphorylation);STAT3转录因子(STAT3 Transcription Factor);T淋巴细胞亚群(T-Lymphocyte Subsets);T淋巴细胞(T-Lymphocytes);结核(Tuberculosis);青年人(Young Adult)

DOI 10.1038/cmi.2018.5

PMID 30886421

发布时间 2024-02-29

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Cellular & molecular immunology

2019年16卷3期

275-287页

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Constitutive STAT3 phosphorylation and IL-6/IL-10 co-expression are associated with impaired T-cell function in tuberculosis patients.

Cellular & molecular immunology

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Cellular & molecular immunology

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Constitutive STAT3 phosphorylation and IL-6/IL-10 co-expression are associated with impaired T-cell function in tuberculosis patients.

Cellular & molecular immunology

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Cellular & molecular immunology

相关期刊

检索历史清除