Inhibition of Ezh2 In Vitro and the Decline of <i>Ezh2</i> in Developing Midbrain Promote Dopaminergic Neurons Differentiation Through Modifying H3K27me3.
第一作者:
Feng,Hong
第一单位:
1 CAS Key Laboratory of Receptor Research, Department of Neuropharmacology, Shanghai Institute of Materia Medica, University of Chinese Academy of Sciences, Shanghai, China.;2 Department of Neuropharmacology, Shanghai Institute of Materia Medica, University of Chinese Academy of Sciences, Beijing, China.
作者:
主题词
动物(Animals);细胞分化(Cell Differentiation);细胞, 培养的(Cells, Cultured);后成说, 遗传(Epigenesis, Genetic);组蛋白脱乙酰基酶抑制剂(Histone Deacetylase Inhibitors);组蛋白类(Histones);吲唑类(Indazoles);赖氨酸(Lysine);中脑(Mesencephalon);甲基化(Methylation);神经干细胞(Neural Stem Cells);核受体亚家族4, A组, 成员2(Nuclear Receptor Subfamily 4, Group A, Member 2);启动区, 遗传(Promoter Regions, Genetic);吡啶酮类(Pyridones);RNA, 小分子干扰(RNA, Small Interfering);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);酪氨酸单氧化酶(Tyrosine 3-Monooxygenase)
DOI
10.1089/scd.2018.0258
PMID
30887911
发布时间
2020-04-30
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Stem cells and development
649-658页
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