RNA polymerase pausing at a protein roadblock can enhance transcriptional interference by promoter occlusion.

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第一作者： Nan,Hao

第一单位： Department of Molecular and Biomedical Science, School of Biological Sciences, The University of Adelaide, Adelaide, Australia.

作者： Nan,Hao ^[1] ; Michael T,Crooks ^[2] ; Adam C,Palmer ^[1] ; Ian B,Dodd ^[3] ; Keith E,Shearwin ^[1]

作者单位： Department of Molecular and Biomedical Science, School of Biological Sciences, The University of Adelaide, Adelaide, Australia. ^[1] CSIRO Synthetic Biology Future Science Platform, Canberra, Australia. ^[2] Department of Systems Biology, Harvard Medical School, Boston, MA, USA. ^[3]

关键词 RNAP pausing bacteriophage mathematical modelling promoter occlusion transcriptional interference transcriptional roadblocking

主题词细菌噬菌体(Bacteriophages);指导DNA的RNA聚合酶类(DNA-Directed RNA Polymerases);基因, 报告(Genes, Reporter);模型, 生物学(Models, Biological);启动区, 遗传(Promoter Regions, Genetic);转录, 遗传(Transcription, Genetic)

DOI 10.1002/1873-3468.13365

PMID 30892685

发布时间 2020-05-15

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