Localization of <sup>99m</sup>Tc-GRP Analogs in GRPR-Expressing Tumors: Effects of Peptide Length and Neprilysin Inhibition on Biological Responses.

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作者： Aikaterini,Kaloudi ^[1] ; Emmanouil,Lymperis ^[2] ; Panagiotis,Kanellopoulos ^[3] ; Beatrice,Waser ^[4] ; Marion,de Jong ^[5] ; Eric P,Krenning ^[6] ; Jean Claude,Reubi ^[7] ; Berthold A,Nock ^[8] ; Theodosia,Maina ^[9]

作者单位： Molecular Radiopharmacy, INRASTES, NCSR "Demokritos", 15310 Athens, Greece. katerinakaloudi@yahoo.gr. ^[1] Molecular Radiopharmacy, INRASTES, NCSR "Demokritos", 15310 Athens, Greece. mlymperis@hotmail.com. ^[2] Molecular Radiopharmacy, INRASTES, NCSR "Demokritos", 15310 Athens, Greece. kanelospan@gmail.com. ^[3] Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Berne, CH-3010 Berne, Switzerland. waserpatho@rubigen.ch. ^[4] Department of Radiology & Nuclear Medicine Erasmus MC, 3015 CN Rotterdam, The Netherlands. m.hendriks-dejong@erasmusmc.nl. ^[5] Cytrotron Rotterdam BV, Erasmus MC, 3015 CN Rotterdam, The Netherlands. erickrenning@gmail.com. ^[6] Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Berne, CH-3010 Berne, Switzerland. jean.reubi@pathology.unibe.ch. ^[7] Molecular Radiopharmacy, INRASTES, NCSR "Demokritos", 15310 Athens, Greece. nock_berthold.a@hotmail.com. ^[8] Molecular Radiopharmacy, INRASTES, NCSR "Demokritos", 15310 Athens, Greece. maina_thea@hotmail.com. ^[9]

关键词 99mTc-radioligand bombesin gastrin-releasing peptide gastrin-releasing peptide receptor metabolic stability neprilysin-inhibition phosphoramidon tumor targeting

DOI 10.3390/ph12010042

PMID 30897789

发布时间 2020-10-01

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