Combined Transcriptomics and Proteomics in Frontal Cortex Area 8 in Frontotemporal Lobar Degeneration Linked to C9ORF72 Expansion.

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作者： Pol,Andrés-Benito ^[1] ; Ellen,Gelpi ^[2] ; Mónica,Povedano ^[3] ; Karina,Ausín ^[4] ; Joaquín,Fernández-Irigoyen ^[5] ; Enrique,Santamaría ^[6] ; Isidro,Ferrer ^[7]

作者单位： Neuropathology, Pathologic Anatomy Service, Bellvitge University Hospital - Bellvitge Biomedical Research Institute (IDIBELL), Hospitalet de Llobregat, Spain. ^[1] Biomedical Network Research Center on Neurodegenerative Diseases (CIBERNED), Institute of Health Carlos III, Hospitalet de Llobregat, Spain. ^[2] Neurological Tissue Bank of the Biobanc-Hospital Clínic-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. ^[3] Institute of Neurology, Medical University of Vienna, Vienna, Austria. ^[4] Functional Unit of Amyotrophic Lateral Sclerosis (UFELA), Service of Neurology, Bellvitge University Hospital, Hospitalet de Llobregat, Spain. ^[5] IDISNA, Navarra Institute for Health Research, Pamplona, Spain. ^[6] Clinical Neuroproteomics group and Proteored-ISCIII, Proteomics Unit, Navarrabiomed, Department of Health, Public University of Navarra, Pamplona, Spain. ^[7] Department of Pathology and Experimental Therapeutics, University of Barcelona, Hospitalet de Llobregat, Spain. ^[8] Institute of Neurosciences, University of Barcelona, Barcelona, Spain. ^[9]

关键词 C9ORF72 FTLD-TDP frontotemporal lobar degeneration gene expression proteomics